Add to ORKGBACKGROUND: Glioblastoma (GBM) is a complex disease with extensive molecular and transcriptional heterogeneity. GBM can be subcategorized into four distinct subtypes; tumors that shift towards the mesenchymal phenotype upon recurrence are generally associated with treatment resistance, unfavorable prognosis, and the infiltration of pro-tumorigenic macrophages. RESULTS: We explore the transcriptional regulatory networks of mesenchymal-associated tumor-associated macrophages (MA-TAMs), which drive the malignant phenotypic state of GBM, and identify macrophage receptor with collagenous structure (MARCO) as the most highly differentially expressed gene. MARCO CONCLUSIONS: Collectively, our study characterizes the global transcriptional profile ...
BackgroundThe main immune cells in GBM are tumor-associated macrophages (TAMs). Thus far, the studie...
BackgroundThe main immune cells in GBM are tumor-associated macrophages (TAMs). Thus far, the studie...
BackgroundThe main immune cells in GBM are tumor-associated macrophages (TAMs). Thus far, the studie...
Background: Glioblastoma (GBM) is a complex disease with extensive molecular and transcriptional het...
Background Glioblastoma (GBM) is a complex disease with extensive molecular and tran...
Background: Glioblastoma (GBM) is a complex disease with extensive molecular and transcriptional het...
Background: Glioblastoma (GBM) is a complex disease with extensive molecular and transcriptional het...
Cancer heterogeneity and progression are subject to complex interactions between neoplastic cells an...
Despite aggressive multimodal treatment, glioblastoma (GBM), a grade IV primary brain tumor, still p...
Glioblastoma (GBM) is the most lethal primary brain tumor characterized by significant cellular hete...
BackgroundThe main immune cells in GBM are tumor-associated macrophages (TAMs). Thus far, the studie...
BackgroundThe main immune cells in GBM are tumor-associated macrophages (TAMs). Thus far, the studie...
Background: Gliomas are one of the most common types of primary tumors in central nervous system. Pr...
BackgroundThe main immune cells in GBM are tumor-associated macrophages (TAMs). Thus far, the studie...
BackgroundThe main immune cells in GBM are tumor-associated macrophages (TAMs). Thus far, the studie...
BackgroundThe main immune cells in GBM are tumor-associated macrophages (TAMs). Thus far, the studie...
BackgroundThe main immune cells in GBM are tumor-associated macrophages (TAMs). Thus far, the studie...
BackgroundThe main immune cells in GBM are tumor-associated macrophages (TAMs). Thus far, the studie...
Background: Glioblastoma (GBM) is a complex disease with extensive molecular and transcriptional het...
Background Glioblastoma (GBM) is a complex disease with extensive molecular and tran...
Background: Glioblastoma (GBM) is a complex disease with extensive molecular and transcriptional het...
Background: Glioblastoma (GBM) is a complex disease with extensive molecular and transcriptional het...
Cancer heterogeneity and progression are subject to complex interactions between neoplastic cells an...
Despite aggressive multimodal treatment, glioblastoma (GBM), a grade IV primary brain tumor, still p...
Glioblastoma (GBM) is the most lethal primary brain tumor characterized by significant cellular hete...
BackgroundThe main immune cells in GBM are tumor-associated macrophages (TAMs). Thus far, the studie...
BackgroundThe main immune cells in GBM are tumor-associated macrophages (TAMs). Thus far, the studie...
Background: Gliomas are one of the most common types of primary tumors in central nervous system. Pr...
BackgroundThe main immune cells in GBM are tumor-associated macrophages (TAMs). Thus far, the studie...
BackgroundThe main immune cells in GBM are tumor-associated macrophages (TAMs). Thus far, the studie...
BackgroundThe main immune cells in GBM are tumor-associated macrophages (TAMs). Thus far, the studie...
BackgroundThe main immune cells in GBM are tumor-associated macrophages (TAMs). Thus far, the studie...
BackgroundThe main immune cells in GBM are tumor-associated macrophages (TAMs). Thus far, the studie...