Correlations of the severity of dyspepsia symptoms with electrogastrography, quality of life and psychological distress : a nested cross-sectional study of functional dyspepsia patients

The pathophysiology of functional dyspepsia (FD) remains unclear, although multiple potential contributors have previously been linked including visceral hypersensitivity, dysregulation of the brain-gut axis from psychological distress, and abnormal gastric myolectrical activity. Expanding upon this, the first aim of this study was to determine whether increasing severity of dyspepsia symptoms in FD patients was associated with abnormal gastric myoelectrical activity as measured by surface electrogastrography (EGG). The second was to determine whether severity of dyspepsia symptoms was associated with quality of life, psychological distress and gastrointestinal symptom-specific anxiety