Radiation inactivation analysis of the binding of the A1 adenosine receptor antagonist, 8-cyclopentyl-1,3-dipropylxanthine to rat brain membranes yielded a radiation inactivation size of 58 kDa. In the presence of GTPyS this was reduced to 33 kDa, in good agreement with the size of the ligand-binding subunit detected after photoaffinity labelling. The data indicate that the structural association of A\(_1\) adenosine receptors with G-protein components is altered in situ in the presence of guanine nucleotides
An orphan G protein-coupled receptor from rat has recently been discovered to be activated by the nu...
Cell membrane is highly sensitive to irradiation which, acting directly or indirectly, may disturb f...
Chronic treatment of rats with R-PIA 'in vivo' desensitized adenosine A1 receptor-mediated inhibitio...
AbstractRadiation inactivation analysis of the binding of the A1 adenosine receptor antagonist, 8-cy...
The effects of guanine nucleotides on binding of 8-cyclopentyl-1,3-[\(^3\)H]dipropylxanthine [\(^3\)...
A\(_1\) adenosine receptors in coated vesicles have been characterized by radioligand binding and ph...
Chemical modification of amino acid residues was used to probe the ligand recognition site of A\(_1\...
The ligand-binding subunit ofthe A1 adenosine receptor has been identified in membranes with the pho...
Adenosine modulates a variety of physiological functions via membrane-bound receptors. These recepto...
The binding of agonists and antagonists to R adenosine receptors of synaptosomal membranes from rat ...
The adenosinergic system is involved in many important physiological functions. Adenosine exerts its...
Radioligand binding to A\(_1\) adenosine receptors at brain membranes from seven species was investi...
A simple method for solubilization and reconstitution of the A1 adenosine receptor from bovine brain...
In striatum and several other tissues, a guanine nucleotide binding protein (G(s)) couples A2 adenos...
We have previously reported that in several renal cell types, adenosine receptor agonists inhibit ad...
An orphan G protein-coupled receptor from rat has recently been discovered to be activated by the nu...
Cell membrane is highly sensitive to irradiation which, acting directly or indirectly, may disturb f...
Chronic treatment of rats with R-PIA 'in vivo' desensitized adenosine A1 receptor-mediated inhibitio...
AbstractRadiation inactivation analysis of the binding of the A1 adenosine receptor antagonist, 8-cy...
The effects of guanine nucleotides on binding of 8-cyclopentyl-1,3-[\(^3\)H]dipropylxanthine [\(^3\)...
A\(_1\) adenosine receptors in coated vesicles have been characterized by radioligand binding and ph...
Chemical modification of amino acid residues was used to probe the ligand recognition site of A\(_1\...
The ligand-binding subunit ofthe A1 adenosine receptor has been identified in membranes with the pho...
Adenosine modulates a variety of physiological functions via membrane-bound receptors. These recepto...
The binding of agonists and antagonists to R adenosine receptors of synaptosomal membranes from rat ...
The adenosinergic system is involved in many important physiological functions. Adenosine exerts its...
Radioligand binding to A\(_1\) adenosine receptors at brain membranes from seven species was investi...
A simple method for solubilization and reconstitution of the A1 adenosine receptor from bovine brain...
In striatum and several other tissues, a guanine nucleotide binding protein (G(s)) couples A2 adenos...
We have previously reported that in several renal cell types, adenosine receptor agonists inhibit ad...
An orphan G protein-coupled receptor from rat has recently been discovered to be activated by the nu...
Cell membrane is highly sensitive to irradiation which, acting directly or indirectly, may disturb f...
Chronic treatment of rats with R-PIA 'in vivo' desensitized adenosine A1 receptor-mediated inhibitio...