Cisplatin is a chemotherapeutic agent widely used in treating various types of cancer. However, its usage is restricted due to the adverse hepatoxicity, as seen in approximately 36% of cancer patients receiving cisplatin treatment. Polygonum minus essential oil has high antioxidant capacity, and is enriched with terpenoids and phenolic compounds. The objective of this study was to investigate effects of P. minus essential oil (PmEO) supplementation on cisplatin-induced hepatotoxicity in rats. Male rats were divided into seven different groups, namely: control (C), cisplatin-induced (CP), positive control with ?-caryophyllene 150 mg/kg (BCP), PmEO 100 mg/kg (PmEO100CP), PmEO 200 mg/kg (PmEO200CP), PmEO 400 mg/kg (PmEO400CP) and PmEO 400 mg/k...
Cisplatin (CP) is a potent anti-cancer drug widely used against solid tumors. However, it exhibits p...
International audienceCisplatin (cis-diamminedichloridoplatinum II [CDDP]) is a chemotherapeutic age...
PubMedID: 16180092Cisplatin, one of the most active cytotoxic agents against cancer, has several tox...
Oxidative stress, inflammation and apoptosis are thought as primary mediators of cisplatin-induced h...
Cisplatin is a chemotherapeutic agent widely used in treating various types of cancer. However, its ...
Cisplatin is a widely used anticancer drug but, it can produce undesirable effects such as hepatotox...
Cisplatin is a widely used anticancer drug but, it can produce undesirable effects such as hepatotox...
Abstract Cisplatin (CP) is considered as a major antineoplastic drug against a broad spectrum of mal...
Cisplatin is a potent platinum-based anticancer drug approved by the Food Drug Administration (FDA) ...
Cisplatin (CP) is a potent anti-cancer drug widely used against solid tumors. However, it exhibits p...
International audienceCisplatin (cis-diamminedichloridoplatinum II [CDDP]) is a chemotherapeutic age...
International audienceCisplatin (cis-diamminedichloridoplatinum II [CDDP]) is a chemotherapeutic age...
International audienceCisplatin (cis-diamminedichloridoplatinum II [CDDP]) is a chemotherapeutic age...
International audienceCisplatin (cis-diamminedichloridoplatinum II [CDDP]) is a chemotherapeutic age...
AbstractCisplatin (CP) is a potent anti-cancer drug widely used against solid tumors. However, it ex...
Cisplatin (CP) is a potent anti-cancer drug widely used against solid tumors. However, it exhibits p...
International audienceCisplatin (cis-diamminedichloridoplatinum II [CDDP]) is a chemotherapeutic age...
PubMedID: 16180092Cisplatin, one of the most active cytotoxic agents against cancer, has several tox...
Oxidative stress, inflammation and apoptosis are thought as primary mediators of cisplatin-induced h...
Cisplatin is a chemotherapeutic agent widely used in treating various types of cancer. However, its ...
Cisplatin is a widely used anticancer drug but, it can produce undesirable effects such as hepatotox...
Cisplatin is a widely used anticancer drug but, it can produce undesirable effects such as hepatotox...
Abstract Cisplatin (CP) is considered as a major antineoplastic drug against a broad spectrum of mal...
Cisplatin is a potent platinum-based anticancer drug approved by the Food Drug Administration (FDA) ...
Cisplatin (CP) is a potent anti-cancer drug widely used against solid tumors. However, it exhibits p...
International audienceCisplatin (cis-diamminedichloridoplatinum II [CDDP]) is a chemotherapeutic age...
International audienceCisplatin (cis-diamminedichloridoplatinum II [CDDP]) is a chemotherapeutic age...
International audienceCisplatin (cis-diamminedichloridoplatinum II [CDDP]) is a chemotherapeutic age...
International audienceCisplatin (cis-diamminedichloridoplatinum II [CDDP]) is a chemotherapeutic age...
AbstractCisplatin (CP) is a potent anti-cancer drug widely used against solid tumors. However, it ex...
Cisplatin (CP) is a potent anti-cancer drug widely used against solid tumors. However, it exhibits p...
International audienceCisplatin (cis-diamminedichloridoplatinum II [CDDP]) is a chemotherapeutic age...
PubMedID: 16180092Cisplatin, one of the most active cytotoxic agents against cancer, has several tox...