Characterization of the Corynebacterium glutamicum deltapimB' deltamgtA double deletion mutant and the role of Mycobacterium tuberculosis orthologues Rv2188c and Rv0557 in glycolipid biosynthesis

In this study, utilizing a Corynebacterium glutamicum DeltapimB' DeltamgtA double deletion mutant, we unequivocally assign the in vivo functions of Rv2188c as an Ac(1)PIM(1):mannosyltransferase (originally termed PimB'(Mt) [Mycobacterium tuberculosis PimB']) and Rv0557 as a GlcAGroAc(2):mannosyltransferase (originally termed PimB(Mt)), which we have reassigned as PimB(Mt) and MgtA(Mt), respectively, in Mycobacterium tuberculosis