ETIOLOGY, CLINICAL PRESENTATION AND EVALUATION OF THE EFFECTIVNESS OF THERAPY IN CHILDREN WITH EPILEPTIC STATUS TREATED AT THE DEPARTMENT OF PEDIATRICS OF THE UNIVERSITY HOSPITAL OF SPLIT FROM 2015 TO 2020

Polovica uključenih ispitanika bila je mlađa od 5,1 godinu, a podjednako su zastupljena oba spola (35, 50% djevojčica naspram 35, 50% dječaka). Nije bilo statističke razlike u dobi između muških i ženskih ispitanika (4 naspram 5,6 godina, p=0,977). Kumulativna incidencija hospitalizacija svih ispitanika iznosi 53,24 na 100000 stanovnika (95% CI 41,5-67,2), odnosno 54,21 na 100000 (95% CI 37,8-75,4) u ženskih ispitanika i 52,30 (95% CI 36,4-72,7) u muških ispitanika. Najveća incidencija ES-a je u dobi 0-4 godine koja je značajno veća u odnosu na više dobne skupine. Dječaci i djevojčice se nisu statistički značajno razlikovali prema komplikacijama u trudnoći (p=0,113), porodu (p=0,282) i ranom perinatalnom periodu (p=0,611) te Apgar zbiru (p=0,592). Nema značajne razlike u trajanja napadaja prema kliničkoj slici (p=0,146), broju napadaja (p=0,225), prvih u odnosu na ponovljene napadaje (p=0,594), terapiji prije prijema (p=0,418), terapiji na prijemu (p=0,163), Apgar zbiru (p=0,283), psihomotornom razvoju (p=0,529) i ponovljenoj terapiji (p=0,629). Ipak, postoji razlika duljine trajanja epileptičkog statusa s obzirom na terapiju koja zaustavlja status (p<0,001). Postoji statistički značajna razlika u trajanju ES između različitih etiologija (p=0,025).Half of the included respondents were younger than 5.1 years, and both sexes were equally represented (35, 50% girls vs. 35, 50% boys). There was no statistical difference in age between male and female subjects (4 vs. 5.6 years, p=0.977). The cumulative incidence of hospitalizations of all subjects was 53.24 per 100,000 population (95% CI 41.5-67.2), or 54.21 per 100,000 (95% CI 37.8-75.4) in female subjects and 52.30 (95% CI 36.4-72.7) in male subjects. The highest incidence of ES is at the age of 0-4 years, which is significantly higher compared to higher age groups. Boys and girls did not differ statistically significantly according to complications in pregnancy (p=0.113), childbirth (p=0.282) and early perinatal period (p=0.611) and Apgar score (p=0.592). There is no significant difference in the duration of seizures according to the clinical picture (p=0.146), the number of seizures (p=0.225), the first in relation to recurrent seizures (p=0.594), therapy before admission (p=0.418), therapy on admission (p=0.163), Apgar score (p=0.283), psychomotor development (p=0.529) and repeated therapy (p=0.629). However, there is a difference in the duration of status epilepticus with respect to status-stopping therapy (p