Add to ORKGWe demonstrate that activation-induced manganese-enhanced magnetic resonance imaging with quantitative determination of the longitudinal relaxation time (qAIM-MRI) reveals the severity of Parkinson’s disease (PD) in mice. We first show that manganese ion-accumulation depends on neuronal activity. A highly active region was then observed by qAIM-MRI in the caudate-putamen in PD-model mice that was significantly correlated to the severity of PD, suggesting its involvement in the expression of PD symptoms
MRI has been extensively used in neurodegenerative disorders, such as Alzheimer’s disease (AD), fron...
Abstract Amyloid plaques are a hallmark of Alzheimer’s disease (AD) that develop in its earliest sta...
none8In activation-induced manganese-enhanced MRI (AIM-MRI) experiments, differential accumulation o...
<p>We demonstrate that activation-induced manganese-enhanced magnetic resonance imaging with quantit...
The neurotoxic effect of manganese (Mn) establishes itself in a condition known as manganism or Mn i...
<div><p>The neurotoxic effect of manganese (Mn) establishes itself in a condition known as <em>manga...
The neurotoxic effect of manganese (Mn) establishes itself in a condition known as manganism or Mn i...
Manganese-enhanced magnetic resonance imaging (MEMRI) is a novel imaging technique capable of monito...
Manganese (Mn), an abundant metal found in soil, air, and many foods is essential for normal body de...
International audienceAlzheimer’s disease (AD) is the most common cause of dementia. Aside neuropath...
Gamma-aminobutyric acid (GABA) is the most abundant inhibitory neurotransmitter in the brain. It pla...
Occupational exposure to Manganese, such as in welding, can cause motor and cognitive deficits that ...
Manganese-enhanced magnetic resonance imaging (MEMRI) is a powerful tool for in vivo non-invasive wh...
Using T1-weighted MRI at two different magnetic field strengths, the enhanced longitudinal relaxivit...
Trace metals are important for proper function of the brain, serving as cofactors for a variety of p...
MRI has been extensively used in neurodegenerative disorders, such as Alzheimer’s disease (AD), fron...
Abstract Amyloid plaques are a hallmark of Alzheimer’s disease (AD) that develop in its earliest sta...
none8In activation-induced manganese-enhanced MRI (AIM-MRI) experiments, differential accumulation o...
<p>We demonstrate that activation-induced manganese-enhanced magnetic resonance imaging with quantit...
The neurotoxic effect of manganese (Mn) establishes itself in a condition known as manganism or Mn i...
<div><p>The neurotoxic effect of manganese (Mn) establishes itself in a condition known as <em>manga...
The neurotoxic effect of manganese (Mn) establishes itself in a condition known as manganism or Mn i...
Manganese-enhanced magnetic resonance imaging (MEMRI) is a novel imaging technique capable of monito...
Manganese (Mn), an abundant metal found in soil, air, and many foods is essential for normal body de...
International audienceAlzheimer’s disease (AD) is the most common cause of dementia. Aside neuropath...
Gamma-aminobutyric acid (GABA) is the most abundant inhibitory neurotransmitter in the brain. It pla...
Occupational exposure to Manganese, such as in welding, can cause motor and cognitive deficits that ...
Manganese-enhanced magnetic resonance imaging (MEMRI) is a powerful tool for in vivo non-invasive wh...
Using T1-weighted MRI at two different magnetic field strengths, the enhanced longitudinal relaxivit...
Trace metals are important for proper function of the brain, serving as cofactors for a variety of p...
MRI has been extensively used in neurodegenerative disorders, such as Alzheimer’s disease (AD), fron...
Abstract Amyloid plaques are a hallmark of Alzheimer’s disease (AD) that develop in its earliest sta...
none8In activation-induced manganese-enhanced MRI (AIM-MRI) experiments, differential accumulation o...