The effect of fibrates (clofibric acid, bezafibrate and fenofibrate) on the gene expression and activity of 1-acylglycerophosphocholine acyltransferase (LPCAT) was investigated. The administration of 0.1% (w/w) clofibric acid, bezafibrate or fenofibrate in diet for 14?d to rats induced LPCAT activity in hepatic microsomes in the following order: fenofibrate>bezafibrate>clofibric acid. The LPCAT induced by fenofibrate preferred to arachidonoyl-CoA and linoleoyl-CoA to a greater extent than did LPCAT in control microsomes. The treatment with the fibrates resulted in upregulation of the relative expression of mRNAs encoding LPCAT3 and LPCAT4 in the following order: fenofibrate>bezafibrate>clofibric acid. The administration of fibrates did not ...
The molecular mechanism by which hypolipidemic fibrates and antidiabetic thiazolidinediones exert th...
A growing body of evidence indicates that peroxisome proliferator-activated receptor alpha (PPAR alp...
The effects of 2-(4-chlorophenoxy)-2-methylpropionic acid (clofibric acid) on the formation of oleic...
The effect of fibrates (clofibric acid, bezafibrate and fenofibrate) on the gene expression and acti...
The administration of fibrates (fenofibrate, bezafibrate and clofibric acid) to rats induced stearoy...
Hepatic triacylglycerol (TAG) homeostasis is maintained by carefully regulated balance between its s...
The influence of different fibrates on apolipoprotein metabolism was investigated. Administration of...
The regulation by fibrates and dietary fatty acids of the hepatic gene expression of apolipopro...
The long-chain acyl-coenzyme A synthetase (ACS) gene gives rise to three transcripts containing diff...
Multienzyme 2-oxoglutarate complex (2-OGDH) together with branched chain ?-ketoacid dehydrogenase (B...
AbstractThe mechanism by which hypolipidemic peroxisome proliferators of the fibrate family induce t...
Several enzymes of the beta-oxidation pathway have been shown to be induced after stimulation with p...
Multienzyme 2-oxoglutarate complex (2-OGDH) together with branched chain \alpha-ketoacid dehydrogen...
The molecular mechanism by which hypolipidemic fibrates and antidiabetic thiazolidinediones exert th...
A growing body of evidence indicates that peroxisome proliferator-activated receptor alpha (PPAR alp...
The effects of 2-(4-chlorophenoxy)-2-methylpropionic acid (clofibric acid) on the formation of oleic...
The effect of fibrates (clofibric acid, bezafibrate and fenofibrate) on the gene expression and acti...
The administration of fibrates (fenofibrate, bezafibrate and clofibric acid) to rats induced stearoy...
Hepatic triacylglycerol (TAG) homeostasis is maintained by carefully regulated balance between its s...
The influence of different fibrates on apolipoprotein metabolism was investigated. Administration of...
The regulation by fibrates and dietary fatty acids of the hepatic gene expression of apolipopro...
The long-chain acyl-coenzyme A synthetase (ACS) gene gives rise to three transcripts containing diff...
Multienzyme 2-oxoglutarate complex (2-OGDH) together with branched chain ?-ketoacid dehydrogenase (B...
AbstractThe mechanism by which hypolipidemic peroxisome proliferators of the fibrate family induce t...
Several enzymes of the beta-oxidation pathway have been shown to be induced after stimulation with p...
Multienzyme 2-oxoglutarate complex (2-OGDH) together with branched chain \alpha-ketoacid dehydrogen...
The molecular mechanism by which hypolipidemic fibrates and antidiabetic thiazolidinediones exert th...
A growing body of evidence indicates that peroxisome proliferator-activated receptor alpha (PPAR alp...
The effects of 2-(4-chlorophenoxy)-2-methylpropionic acid (clofibric acid) on the formation of oleic...