Phenylpropanoids may act as nonsteroidal anti-inflammatory drug (NSAID)-like compounds. 4-cis,8-cis-Bis(4-hydroxy-3-methoxyphenyl)-3,7-dioxabicyclo-[3.3.0]octane-2,6-dione (bis-FA, compound 2), a dimer of ferulic acid, was synthesized from ferulic acid (1), and its effect on lipopolysaccharide (LPS)-stimulated cyclooxygenase-2 (COX-2) expression in RAW 264.7 cells was compared with those of the parent ferulic acid (1) and of iso-ferulic acid (3-hydroxy-4-methoxycinnamic acid) (3). LPS-induced gene expression of COX-2 was markedly inhibited by compound 2 at a concentration of 10 μM and by compound 3 at 100 μM, but was not inhibited by compound 1 at 100 μM. This observation suggests that compound 2 may possess potent anti-inflammatory activit...
Nonsteroidal anti-inflammatory drugs (NSAIDs) are a family of COX1 and COX2 inhibitors used to reduc...
International audienceIntroduction New fluorinated diaryl ethers and bisarylic ketones were designed...
BACKGROUND: Nonsteroidal anti-inflammatory drugs (NSAIDs) are a family of COX1 and COX2 inhibitors u...
Phenylpropanoids may act as nonsteroidal anti-inflammatory drug (NSAID)-like compounds. 4-cis,8-cis-...
Selective cyclooxygenase (COX)-2 inhibitors have attracted much attention in relation to the design ...
AbstractThe ferulic and gallic acid related compounds from natural origin were studied against xanth...
BackgroundEthyl ferulate (EF) is a derivative of ferulic acid (FA), which is a monomeric component p...
Various factors such as ultraviolet rays can cause a continuous threat to our skin, resulting in inf...
Ferulic acid (FA) is a polyphenol pertaining to the class of hydroxycinnamic acids present in numero...
Ferulic acid (FA) is a polyphenol pertaining to the class of hydroxycinnamic acids present in numero...
Ferulic acid is a phenolic acid widely distributed in the plant kingdom. It presents a wide range of...
Ferulic acid, a well-known natural phenolic compound, is considerably reportedfor its hydroxyl and p...
The Ugi four-component reaction employing naturally occurred ferulic acid (FA) is proposed as a conv...
Cyclooxygenases (COXs) are the key enzymes in the biosynthesis of prostanoids. COX-1 is a constituti...
Background:Ferulic Acid (FA) is a phenolic compound that exhibits a wide range of therapeutic effect...
Nonsteroidal anti-inflammatory drugs (NSAIDs) are a family of COX1 and COX2 inhibitors used to reduc...
International audienceIntroduction New fluorinated diaryl ethers and bisarylic ketones were designed...
BACKGROUND: Nonsteroidal anti-inflammatory drugs (NSAIDs) are a family of COX1 and COX2 inhibitors u...
Phenylpropanoids may act as nonsteroidal anti-inflammatory drug (NSAID)-like compounds. 4-cis,8-cis-...
Selective cyclooxygenase (COX)-2 inhibitors have attracted much attention in relation to the design ...
AbstractThe ferulic and gallic acid related compounds from natural origin were studied against xanth...
BackgroundEthyl ferulate (EF) is a derivative of ferulic acid (FA), which is a monomeric component p...
Various factors such as ultraviolet rays can cause a continuous threat to our skin, resulting in inf...
Ferulic acid (FA) is a polyphenol pertaining to the class of hydroxycinnamic acids present in numero...
Ferulic acid (FA) is a polyphenol pertaining to the class of hydroxycinnamic acids present in numero...
Ferulic acid is a phenolic acid widely distributed in the plant kingdom. It presents a wide range of...
Ferulic acid, a well-known natural phenolic compound, is considerably reportedfor its hydroxyl and p...
The Ugi four-component reaction employing naturally occurred ferulic acid (FA) is proposed as a conv...
Cyclooxygenases (COXs) are the key enzymes in the biosynthesis of prostanoids. COX-1 is a constituti...
Background:Ferulic Acid (FA) is a phenolic compound that exhibits a wide range of therapeutic effect...
Nonsteroidal anti-inflammatory drugs (NSAIDs) are a family of COX1 and COX2 inhibitors used to reduc...
International audienceIntroduction New fluorinated diaryl ethers and bisarylic ketones were designed...
BACKGROUND: Nonsteroidal anti-inflammatory drugs (NSAIDs) are a family of COX1 and COX2 inhibitors u...