Сomorbidity profile in chronicbrain ischemia on the backgroundof multifocal atherosclerosis

Abstract. Comorbidity profile in chronic brain ischemia on the background of multifocal atherosclerosis.Dzyak L.А., Rosytska О.А. Aim to evaluate the comorbidity profile in patients with chronic cerebral ischemia on thebackground of multifocal atherosclerosis. The study included 137 patients aged 40 to 84 years with chronic cerebralischemia (CСI) on the background of multifocal atherosclerosis, which were divided into three clinical groupsdepending on the localization of vascular lesions by stenosing atherosclerosis. The co-morbidity profile and severitywere evaluated using the Charlson’s index in modification of R.A. Deyo (1992). In CCI patients, regardless of thecombination of vascular basins affected by atherosclerosis, a severe degree of comorbidity prevailed - the Charlson’scomorbidity index (IC) was predominantly > 5 points (84.7% of cases). In the analysis of IC in age categories,depending on the combination of atherosclerotic lesions of the vascular basins, it was found that comorbidity of severedegree (IC> 5) was predominantly represented by patients of the older age group (60-74 years), and comorbidity ofmoderate severity (IC≤5) – patients of middle age group (45-59 years). A median difference of 3 points in assessing themean value of age-matched comorbidity index showed that age, as a non-modifiable risk factor, in 1/3 cases determinesthe comorbidity index, which depends on the number of vascular basins affected by atherosclerosis. In 2/3 of the casesit is a modified comorbid pathology. Assessment of IC in clinical groups, taking into account the nature of the diseasecourse (p