Associations of total and free 25OHD and 1,25(OH)2D with serum markers of inflammation in older men
- Srikanth, P
- Chun, R F
- Hewison, M
- Adams, J S
- Bouillon, Roger
- Vanderschueren, Dirk
- Lane, N
- Cawthon, P M
- Dam, T
- Barrett-Connor, E
- Daniels, L B
- Shikany, J M
- Stefanick, M L
- Cauley, J A
- Orwoll, E S
- Nielson, C M
Publication date
July 2016
DOI Publisher
Springer International ISSN
0937-941X Journal
issn:0937-941X Citation count (estimate)
9Abstract
Vitamin D is hypothesized to suppress inflammation. We tested total and free vitamin D metabolites and their association with inflammatory markers. Interleukin-6 levels were lower with higher 25-hydroxyvitamin D. 1,25-dihydroxyvitamin D and free 25OHD associations mirrored those of 25OHD. However, associations for the two metabolites diverged for tumor necrosis factor alpha (TNF-α) soluble receptors.status: publishe
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