Rickettsia felis, the etiologic agent of spotted fever, is maintained in cat fleas by vertical transmission and resembles other tick-borne spotted fever group rickettsiae. In the present study, we utilized an Ixodes scapularis-derived tick cell line, ISE6, to achieve isolation and propagation of R. felis. A cytopathic effect of increased vacuolization was commonly observed in R. felis-infected cells, while lysis of host cells was not evident despite large numbers of rickettsiae. Electron microscopy identified rickettsia-like organisms in ISE6 cells, and sequence analyses of portions of the citrate synthase (gltA), 16S rRNA, Rickettsia genus-specific 17-kDa antigen, and spotted fever group-specific outer membrane protein A (ompA) genes and, ...
Evidence of spotted fever group (SFG) rickettsiae was obtained from flea pools and individual ticks ...
BACKGROUND: Since its first detection, characterization of R. felis has been a matter of debate, mos...
The present study evaluated the rickettsial infection in a laboratory colony of cat fleas, Ctenoceph...
Rickettsial diversity is intriguing in that some species are transmissible to vertebrates, while oth...
Rickettsia felis, a flea-associated rickettsial pathogen, has been identified in many tissues, inclu...
A study was performed to determine the life cycle of Rickettsia felis, a novel bacterium associated ...
Background: Cat fleas, Ctenocephalides felis, are known biological vectors for Rickettsia felis. Ric...
Fleas serve as arthropod vectors for several emerging and re-emerging infectious disease causing age...
Evidence for horizontal routes of transmission for Rickettsia felis has come from detection of R. fe...
Rickettsia felis was described as a human pathogen almost two decades ago, and human infection is cu...
The present study evaluated the rickettsial infection in a laboratory colony of cat fleas, Ctenoceph...
Background: Rickettsia felis is a flea-associated rickettsial pathogen recurrently identified in bot...
Rickettsial diversity is intriguing in that some species are transmissible to vertebrates, while oth...
BACKGROUND: Since its first detection, characterization of R. felis has been a matter of debate, mos...
ABSTRACT It has been two decades since the Þrst description of Rickettsia felis, and although a near...
Evidence of spotted fever group (SFG) rickettsiae was obtained from flea pools and individual ticks ...
BACKGROUND: Since its first detection, characterization of R. felis has been a matter of debate, mos...
The present study evaluated the rickettsial infection in a laboratory colony of cat fleas, Ctenoceph...
Rickettsial diversity is intriguing in that some species are transmissible to vertebrates, while oth...
Rickettsia felis, a flea-associated rickettsial pathogen, has been identified in many tissues, inclu...
A study was performed to determine the life cycle of Rickettsia felis, a novel bacterium associated ...
Background: Cat fleas, Ctenocephalides felis, are known biological vectors for Rickettsia felis. Ric...
Fleas serve as arthropod vectors for several emerging and re-emerging infectious disease causing age...
Evidence for horizontal routes of transmission for Rickettsia felis has come from detection of R. fe...
Rickettsia felis was described as a human pathogen almost two decades ago, and human infection is cu...
The present study evaluated the rickettsial infection in a laboratory colony of cat fleas, Ctenoceph...
Background: Rickettsia felis is a flea-associated rickettsial pathogen recurrently identified in bot...
Rickettsial diversity is intriguing in that some species are transmissible to vertebrates, while oth...
BACKGROUND: Since its first detection, characterization of R. felis has been a matter of debate, mos...
ABSTRACT It has been two decades since the Þrst description of Rickettsia felis, and although a near...
Evidence of spotted fever group (SFG) rickettsiae was obtained from flea pools and individual ticks ...
BACKGROUND: Since its first detection, characterization of R. felis has been a matter of debate, mos...
The present study evaluated the rickettsial infection in a laboratory colony of cat fleas, Ctenoceph...