RNA Polymerase II (Pol II) is responsible for transcribing all protein coding genes and some non-coding genes. Protein-coding mRNAs undergo extensive processing during Pol II transcription in order to become functional molecules. This includes 5’capping, splicing and 3’end cleavage and polyadenylation. mRNA processing is coordinated by the phosphorylation of the Pol II carboxy-terminal domain (CTD) and has been shown to be affected by transcription rate. However, the molecular mechanisms underpinning regulation of mRNA processing by transcription are not well understood. Here, I aim to address this by establishing an in vitro system which allows to the study of processes linked to transcription such as mRNA 3’ end processing. The work pres...
RNA Polymerase II (Pol II) transcribes mRNA genes, snRNA genes and histone genes. Whereas mRNA genes...
RNA processing is carried out in close proximity to the site of transcription, suggesting a regulato...
The process of transcription, in which DNA is converted to RNA, is an integral process in the expres...
Transcription by RNA polymerase II (Pol II) is one of the most highly regulated processes within the...
Thesis (Ph.D.)--University of Washington, 2013RNA Polymerase II (PolII) dependent transcription of m...
Recent advances in sequencing techniques that measure nascent transcripts and that reveal the positi...
Recent advances in sequencing techniques that measure nascent transcripts and that reveal the positi...
Recent advances in sequencing techniques that measure nascent transcripts and that reveal the positi...
Recent advances in sequencing techniques that measure nascent transcripts and that reveal the positi...
Recent advances in sequencing techniques that measure nascent transcripts and that reveal the positi...
Recent advances in sequencing techniques that measure nascent transcripts and that reveal the positi...
RNA processing is carried out in close proximity to the site of transcription, suggesting a regulato...
RNA processing is carried out in close proximity to the site of transcription, suggesting a regulato...
AbstractA large body of work has proved that transcription by RNA polymerase II and pre-mRNA process...
RNA processing is carried out in close proximity to the site of transcription, suggesting a regulato...
RNA Polymerase II (Pol II) transcribes mRNA genes, snRNA genes and histone genes. Whereas mRNA genes...
RNA processing is carried out in close proximity to the site of transcription, suggesting a regulato...
The process of transcription, in which DNA is converted to RNA, is an integral process in the expres...
Transcription by RNA polymerase II (Pol II) is one of the most highly regulated processes within the...
Thesis (Ph.D.)--University of Washington, 2013RNA Polymerase II (PolII) dependent transcription of m...
Recent advances in sequencing techniques that measure nascent transcripts and that reveal the positi...
Recent advances in sequencing techniques that measure nascent transcripts and that reveal the positi...
Recent advances in sequencing techniques that measure nascent transcripts and that reveal the positi...
Recent advances in sequencing techniques that measure nascent transcripts and that reveal the positi...
Recent advances in sequencing techniques that measure nascent transcripts and that reveal the positi...
Recent advances in sequencing techniques that measure nascent transcripts and that reveal the positi...
RNA processing is carried out in close proximity to the site of transcription, suggesting a regulato...
RNA processing is carried out in close proximity to the site of transcription, suggesting a regulato...
AbstractA large body of work has proved that transcription by RNA polymerase II and pre-mRNA process...
RNA processing is carried out in close proximity to the site of transcription, suggesting a regulato...
RNA Polymerase II (Pol II) transcribes mRNA genes, snRNA genes and histone genes. Whereas mRNA genes...
RNA processing is carried out in close proximity to the site of transcription, suggesting a regulato...
The process of transcription, in which DNA is converted to RNA, is an integral process in the expres...