Add to ORKGWe aimed to combine evidence from all heart failure trials that have investigated the effects of drugs with blood pressure (BP)-lowering properties to assess the extent to which such drugs reduce BP in heart failure, the association between the net change in BP between treatment arms and cause-specific outcomes and whether treatment effects (efficacy and safety) vary according to baseline BP. We conducted a systematic review and meta-analysis including randomized clinical trials of drugs with BP-lowering properties in patients with chronic heart failure with at least 300 patient-years follow-up. We included a total of 37 trials (91 950 patients) and showed that treatment with drugs with BP-lowering properties resulted in a small but signifi...
Objectives To assess the effect of antihypertensive treatment in the 130-140mm Hg systolic blood pre...
Objective To define the cardiovascular effects of lowering blood pressure in people with chronic kid...
Background Cardiovascular disease is a leading cause of mortality and morbidity worldwide. Blood p...
The benefits of blood pressure lowering treatment for prevention of cardiovascular disease are well ...
Hypertension is a common comorbidity in patients with heart failure and most drugs that have demonst...
Background The benefits of reducing blood pressure are well established, but there remains uncertain...
Background The benefits of reducing blood pressure are well established, but there remains uncertain...
Introduction Previous research from the Blood Pressure Lowering Treatment Trialists' Collaboration (...
Background: The benefits of reducing blood pressure are well established, but there remains uncertai...
Background Elevated blood pressure is one of the major preventable causes of premature morbidity and...
Objective Evidence from randomised trials of pharmacological treatments on long-term blood pressure ...
Objective: To assess the clinical relevance of regression to the mean for clinical trials and clinic...
In a quantitative overview of published trials, we investigated whether pharmacologic properties of ...
survival in chronic heart failure To the editor: I read with great interest the paper by Raphael et ...
Background Randomised evidence on the efficacy of blood pressure (BP)-lowering treatment to reduce c...
Objectives To assess the effect of antihypertensive treatment in the 130-140mm Hg systolic blood pre...
Objective To define the cardiovascular effects of lowering blood pressure in people with chronic kid...
Background Cardiovascular disease is a leading cause of mortality and morbidity worldwide. Blood p...
The benefits of blood pressure lowering treatment for prevention of cardiovascular disease are well ...
Hypertension is a common comorbidity in patients with heart failure and most drugs that have demonst...
Background The benefits of reducing blood pressure are well established, but there remains uncertain...
Background The benefits of reducing blood pressure are well established, but there remains uncertain...
Introduction Previous research from the Blood Pressure Lowering Treatment Trialists' Collaboration (...
Background: The benefits of reducing blood pressure are well established, but there remains uncertai...
Background Elevated blood pressure is one of the major preventable causes of premature morbidity and...
Objective Evidence from randomised trials of pharmacological treatments on long-term blood pressure ...
Objective: To assess the clinical relevance of regression to the mean for clinical trials and clinic...
In a quantitative overview of published trials, we investigated whether pharmacologic properties of ...
survival in chronic heart failure To the editor: I read with great interest the paper by Raphael et ...
Background Randomised evidence on the efficacy of blood pressure (BP)-lowering treatment to reduce c...
Objectives To assess the effect of antihypertensive treatment in the 130-140mm Hg systolic blood pre...
Objective To define the cardiovascular effects of lowering blood pressure in people with chronic kid...
Background Cardiovascular disease is a leading cause of mortality and morbidity worldwide. Blood p...