BACKGROUND The World Health Organization recommends not performing transfusions in African children hospitalized for uncomplicated severe anemia (hemoglobin level of 4 to 6 g per deciliter and no signs of clinical severity). However, high mortality and readmission rates suggest that less restrictive transfusion strategies might improve outcomes. METHODS In this factorial, open-label, randomized, controlled trial, we assigned Ugandan and Malawian children 2 months to 12 years of age with uncomplicated severe anemia to immediate transfusion with 20 ml or 30 ml of whole-blood equivalent per kilogram of body weight, as determined in a second simultaneous randomization, or no immediate transfusion (control group), in which transfusion with 20 m...
Background: The World Health Organization recommends a haemoglobin transfusion threshold of 0.2) nor...
Symptomatic severe malarial anaemia (SMA) has a high fatality rate of 30-40%; most deaths occur in c...
The phase III Transfusion and Treatment of severe anaemia in African Children Trial(TRACT) found tha...
BACKGROUND The World Health Organization recommends not performing transfusions in African children ...
Background The World Health Organization recommends not performing transfusions in African children ...
BACKGROUND Severe anemia (hemoglobin level, ≺6 g per deciliter) is a leading cause of hospital admis...
BACKGROUND Severe anemia (hemoglobin level, \u3c6 g per deciliter) is a leading cause of hospital ad...
Background In sub-Saharan Africa, where infectious diseases and nutritional deficiencies are common,...
Background: Owing to inadequate supplies of donor blood for transfusion in sub-Saharan Africa (sSA) ...
Background Severe anaemia in children is a leading cause of hospital admission and a major cause of ...
BACKGROUND: In sub-Saharan Africa, where infectious diseases and nutritional deficiencies are common...
BACKGROUND: Severe anaemia requiring emergency blood transfusion is a common complication of malaria...
Background: Severe anaemia requiring emergency blood transfusion is a common complication of malaria...
BACKGROUND: Severe anemia (SA, hemoglobin 6 g/dl: primary outcome) and 28-day survival. RESULTS: Med...
SummaryBackgroundIn sub-Saharan Africa, children are frequently admitted with severe anaemia needing...
Background: The World Health Organization recommends a haemoglobin transfusion threshold of 0.2) nor...
Symptomatic severe malarial anaemia (SMA) has a high fatality rate of 30-40%; most deaths occur in c...
The phase III Transfusion and Treatment of severe anaemia in African Children Trial(TRACT) found tha...
BACKGROUND The World Health Organization recommends not performing transfusions in African children ...
Background The World Health Organization recommends not performing transfusions in African children ...
BACKGROUND Severe anemia (hemoglobin level, ≺6 g per deciliter) is a leading cause of hospital admis...
BACKGROUND Severe anemia (hemoglobin level, \u3c6 g per deciliter) is a leading cause of hospital ad...
Background In sub-Saharan Africa, where infectious diseases and nutritional deficiencies are common,...
Background: Owing to inadequate supplies of donor blood for transfusion in sub-Saharan Africa (sSA) ...
Background Severe anaemia in children is a leading cause of hospital admission and a major cause of ...
BACKGROUND: In sub-Saharan Africa, where infectious diseases and nutritional deficiencies are common...
BACKGROUND: Severe anaemia requiring emergency blood transfusion is a common complication of malaria...
Background: Severe anaemia requiring emergency blood transfusion is a common complication of malaria...
BACKGROUND: Severe anemia (SA, hemoglobin 6 g/dl: primary outcome) and 28-day survival. RESULTS: Med...
SummaryBackgroundIn sub-Saharan Africa, children are frequently admitted with severe anaemia needing...
Background: The World Health Organization recommends a haemoglobin transfusion threshold of 0.2) nor...
Symptomatic severe malarial anaemia (SMA) has a high fatality rate of 30-40%; most deaths occur in c...
The phase III Transfusion and Treatment of severe anaemia in African Children Trial(TRACT) found tha...