Add to ORKGNovel amidinourea derivatives have been synthesised and evaluated for their antiviral activity against Hepatitis C Virus (HCV). A compound with an amidinourea-spermine chemical structure, different from that of standard anti-HCV drugs, showed micromolar activity against HCV and excellent viability. Studies on the mode of action revealed that the new compound may act against HCV through the inhibition of IRES-mediated translation
Hepatitis C virus (HCV), the etiological agent of the most common and dangerous diseases of the live...
Our study describes the discovery of a series of highly potent hepatitis C virus (HCV) NS5A inhibito...
Substituted 5-benzyl-2-phenyl-5H-imidazo[4,5-c]pyridines represent a novel class of compounds with a...
Novel amidinourea derivatives have been synthesised and evaluated for their antiviral activity again...
The discovery of a novel class of HCV inhibitors is described. The new amidinourea compounds were de...
Current therapy against herpes simplex viruses (HSV) relies on the use of a few nucleoside antiviral...
HCMV infection represents a life-threatening condition for immunocompromised patients and newborn in...
Aminoquinolines and piperazines, linked or not, have been used successfully to treat malaria, and so...
International audienceAminoquinolines and piperazines, linked or not, have been used successfully to...
Synthesis and anti-hepatitis C virus (anti-HCV) effects of certain 3-amino-2-hydroxy-propoxy isoflav...
Hepatitis C virus (HCV) infection can cause serious liver disease. Efforts to eliminate the virus in...
Heat-stress cognate 70 (Hsc70) is a host factor that helps hepatitis C virus (HCV) to complete its l...
In view of a persistent threat to mankind, the development of nucleotide-based prodrugs against hepa...
AbstractA series of novel amino-substituted N-aryl benzamide analogs were synthesized and evaluated ...
Hepatitis C virus (HCV) NS3/NS4A serine protease is essential for viral replication, which is regard...
Hepatitis C virus (HCV), the etiological agent of the most common and dangerous diseases of the live...
Our study describes the discovery of a series of highly potent hepatitis C virus (HCV) NS5A inhibito...
Substituted 5-benzyl-2-phenyl-5H-imidazo[4,5-c]pyridines represent a novel class of compounds with a...
Novel amidinourea derivatives have been synthesised and evaluated for their antiviral activity again...
The discovery of a novel class of HCV inhibitors is described. The new amidinourea compounds were de...
Current therapy against herpes simplex viruses (HSV) relies on the use of a few nucleoside antiviral...
HCMV infection represents a life-threatening condition for immunocompromised patients and newborn in...
Aminoquinolines and piperazines, linked or not, have been used successfully to treat malaria, and so...
International audienceAminoquinolines and piperazines, linked or not, have been used successfully to...
Synthesis and anti-hepatitis C virus (anti-HCV) effects of certain 3-amino-2-hydroxy-propoxy isoflav...
Hepatitis C virus (HCV) infection can cause serious liver disease. Efforts to eliminate the virus in...
Heat-stress cognate 70 (Hsc70) is a host factor that helps hepatitis C virus (HCV) to complete its l...
In view of a persistent threat to mankind, the development of nucleotide-based prodrugs against hepa...
AbstractA series of novel amino-substituted N-aryl benzamide analogs were synthesized and evaluated ...
Hepatitis C virus (HCV) NS3/NS4A serine protease is essential for viral replication, which is regard...
Hepatitis C virus (HCV), the etiological agent of the most common and dangerous diseases of the live...
Our study describes the discovery of a series of highly potent hepatitis C virus (HCV) NS5A inhibito...
Substituted 5-benzyl-2-phenyl-5H-imidazo[4,5-c]pyridines represent a novel class of compounds with a...