Concordance in anti-OmpC and anti-I2 indicate the influence of genetic predisposition, results of a European study of twins with Crohn's disease
- Amcoff, Karin
- Joossens, Marie
- Pierik, Marie J
- Jonkers, Daisy
- Bohr, Johan
- Joossens, Sofie
- Romberg-Camps, Mariëlle
- Nyhlin, Nils
- Wickbom, Anna
- Rutgeerts, Paul J
- Tysk, Curt
- Bodin, Lennart
- Colombel, Jean-Frederic
- Vermeire, Séverine
- Halfvarson, Jonas
Publication date
June 2016
DOI Publisher
Elsevier Science BV ISSN
1873-9946 Journal
issn:1873-9946 Citation count (estimate)
2Abstract
An adaptive immunologic response to microbial antigens has been observed in Crohn's disease (CD). Intriguingly, this serologic response precedes the diagnosis in some patients and has also been observed in healthy relatives. We aimed to determine whether genetic factors are implicated in this response in a CD twin cohort.status: publishe
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