Add to ORKGAttempts to elucidate the roles of carbohydrate-associated structures in biology have led to the distinct field of glycobiology research. The focus of this field has been in understanding the evolution, biosynthesis and interactions of glycans, both individually and as components of larger biomolecules. However, as most approaches for studying glycans (including mass spectrometry and various binding assays) use ensemble measurements, they lack the precision required to uncover the discrete roles of glycoconjugates, which are often heterogeneous, in biomolecular processes. Single-molecule techniques can examine individual events within challenging mixtures, and they are beginning to be applied to glycobiology. For example, single-molecule fo...
Glycans are one of the four major building blocks of life, along with nucleic acids, proteins, and l...
During the last three decades, a series of key technological improvements turned atomic force micros...
Imaging of biomolecules guides our understanding of their diverse structures and functions1,2. Real-...
Attempts to elucidate the roles of carbohydrate-associated structures in biology have led to the dis...
A crucial challenge in cell biology is to understand how cell surface-associated molecules are organ...
The past years have witnessed remarkable advances in our use of atomic force microscopy (AFM) for st...
Cells encode information in the sequence of biopolymers, such as nucleic acids, proteins, and glycan...
Most lectins bind carbohydrate ligands with relatively low affinity, making the identification of op...
The nanoscale exploration of microbes using atomic force microscopy (AFM) is an exciting, rapidly ev...
Glycans are among the most intriguing carriers of biological information in living systems. The stru...
Carbohydrate chemistry evolved into carbohydrate biochemistry and gradually into the biology of carb...
Glycans are central to many biological processes, but efforts to define their functions at the molec...
The nanoscale exploration of microbes using atomic force microscopy (AFM) is an exciting, rapidly ev...
Abstract Imaging biomolecules in real space is crucial for gaining a comprehensive understanding of ...
Most microbes are coated with carbohydrates that show remarkable structural variability and play a c...
Glycans are one of the four major building blocks of life, along with nucleic acids, proteins, and l...
During the last three decades, a series of key technological improvements turned atomic force micros...
Imaging of biomolecules guides our understanding of their diverse structures and functions1,2. Real-...
Attempts to elucidate the roles of carbohydrate-associated structures in biology have led to the dis...
A crucial challenge in cell biology is to understand how cell surface-associated molecules are organ...
The past years have witnessed remarkable advances in our use of atomic force microscopy (AFM) for st...
Cells encode information in the sequence of biopolymers, such as nucleic acids, proteins, and glycan...
Most lectins bind carbohydrate ligands with relatively low affinity, making the identification of op...
The nanoscale exploration of microbes using atomic force microscopy (AFM) is an exciting, rapidly ev...
Glycans are among the most intriguing carriers of biological information in living systems. The stru...
Carbohydrate chemistry evolved into carbohydrate biochemistry and gradually into the biology of carb...
Glycans are central to many biological processes, but efforts to define their functions at the molec...
The nanoscale exploration of microbes using atomic force microscopy (AFM) is an exciting, rapidly ev...
Abstract Imaging biomolecules in real space is crucial for gaining a comprehensive understanding of ...
Most microbes are coated with carbohydrates that show remarkable structural variability and play a c...
Glycans are one of the four major building blocks of life, along with nucleic acids, proteins, and l...
During the last three decades, a series of key technological improvements turned atomic force micros...
Imaging of biomolecules guides our understanding of their diverse structures and functions1,2. Real-...