Add to ORKGCurrently, Alzheimer’s disease (AD) has no cure. Using a rat AD model, we identified aberrantly expressed proteins during pre-pathology as potential biomarkers. The expression of certain biomarkers was reversed by diazoxide, a repurposed hypertension drug. These results suggest that drug repurposing at an early stage of AD has therapeutic potential
Alzheimer’s Disease (AD) affects over 5.8 million people in the United States each year. This number...
Background: Memory disorders have been characterized by being a devastating long term incurable dise...
Our hypothesis is that changes in gene and protein expression are crucial to the development of late...
Currently, Alzheimer’s disease (AD) has no cure. Using a rat AD model, we identified aberrantly expr...
The purpose of this study was to measure the expression levels of key signaling proteins in brain ti...
Alzheimer’s disease (AD) is characterized by the prion-like propagation of misfolded proteins that a...
Microglia are the resident immune cells of the CNS and constitute about 10% of all cells in the CNS....
Alzheimer’s disease (AD) is a complex multifactorial disorder with poorly characterized pathogenesis...
Alzheimer’s disease (AD) is a neurodegenerative disease which is pathologically characterized by ext...
The complex pathology of Alzheimer’s disease (AD) emphasises the need for comprehensive modelling of...
abstract: Memory loss is the most profound clinical manifestation in Alzheimer’s disease (AD); howev...
Prior to beta-amyloid (Aβ) protein accumulation into plaques in Alzheimer’s disease (AD), neuroinfla...
The onset and progression of Alzheimer’s disease (AD) is characterised by increasing intracellular a...
Altres ajuts: CIBERNED CB06/05/0042 i BrightFocus Foundation (A2014417S)Alzheimer's disease (AD) is ...
Alzheimer's disease (AD) is the most prevalent neurodegenerative disorder in the US, affecting over ...
Alzheimer’s Disease (AD) affects over 5.8 million people in the United States each year. This number...
Background: Memory disorders have been characterized by being a devastating long term incurable dise...
Our hypothesis is that changes in gene and protein expression are crucial to the development of late...
Currently, Alzheimer’s disease (AD) has no cure. Using a rat AD model, we identified aberrantly expr...
The purpose of this study was to measure the expression levels of key signaling proteins in brain ti...
Alzheimer’s disease (AD) is characterized by the prion-like propagation of misfolded proteins that a...
Microglia are the resident immune cells of the CNS and constitute about 10% of all cells in the CNS....
Alzheimer’s disease (AD) is a complex multifactorial disorder with poorly characterized pathogenesis...
Alzheimer’s disease (AD) is a neurodegenerative disease which is pathologically characterized by ext...
The complex pathology of Alzheimer’s disease (AD) emphasises the need for comprehensive modelling of...
abstract: Memory loss is the most profound clinical manifestation in Alzheimer’s disease (AD); howev...
Prior to beta-amyloid (Aβ) protein accumulation into plaques in Alzheimer’s disease (AD), neuroinfla...
The onset and progression of Alzheimer’s disease (AD) is characterised by increasing intracellular a...
Altres ajuts: CIBERNED CB06/05/0042 i BrightFocus Foundation (A2014417S)Alzheimer's disease (AD) is ...
Alzheimer's disease (AD) is the most prevalent neurodegenerative disorder in the US, affecting over ...
Alzheimer’s Disease (AD) affects over 5.8 million people in the United States each year. This number...
Background: Memory disorders have been characterized by being a devastating long term incurable dise...
Our hypothesis is that changes in gene and protein expression are crucial to the development of late...