Antibodies are proteins of the immune system that are able to bind to a huge variety of different substances, making them attractive candidates for therapeutic applications. Antibody structures have the potential to be useful during drug development, allowing the implementation of rational design procedures. The most challenging part of the antibody structure to experimentally determine or model is the H3 loop, which in addition is often the most important region in an antibody's binding site. This review summarises the approaches used so far in the pursuit of accurate computational H3 structure prediction
Antibodies are an essential part of the immune system. They are able to attain high specificity and...
AbstractFor the third complementarity determining region of the antibody heavy chain (CDR-H3), we pr...
Antibodies are proteins of the adapative immune system. Structural diversity in an antibody's two va...
Antibodies are proteins of the immune system that are able to bind to a huge variety of different su...
Antibodies are important immunological molecules that can bind a diverse array of foreign molecules....
The H3 loop in the Complementary Determining Region (CDR) of antibodies plays a key role in their ab...
The H3 loop in the Complementary Determining Region (CDR) of antibodies plays a key role in their ab...
Motivation: Antibodies are able to recognize a wide range of antigens through their complementary de...
Protein structure prediction has gained increased attention over the past decades in a wide range of...
Loops are often vital for protein function, and therefore accurate prediction of their structures is...
So far the difficulty to predict the structure of the third hypervariable loop of the heavy chain of...
Antibodies are soluble proteins produced by the adaptive immune system to bind and counteract invadi...
Antibodies are soluble proteins produced by the adaptive immune system to bind and counteract invadi...
'To whom correspondence should be addressed The structure of the most variable antibody hyperva...
Antibodies are proteins that are the recognition elements of the immune system and increasingly used...
Antibodies are an essential part of the immune system. They are able to attain high specificity and...
AbstractFor the third complementarity determining region of the antibody heavy chain (CDR-H3), we pr...
Antibodies are proteins of the adapative immune system. Structural diversity in an antibody's two va...
Antibodies are proteins of the immune system that are able to bind to a huge variety of different su...
Antibodies are important immunological molecules that can bind a diverse array of foreign molecules....
The H3 loop in the Complementary Determining Region (CDR) of antibodies plays a key role in their ab...
The H3 loop in the Complementary Determining Region (CDR) of antibodies plays a key role in their ab...
Motivation: Antibodies are able to recognize a wide range of antigens through their complementary de...
Protein structure prediction has gained increased attention over the past decades in a wide range of...
Loops are often vital for protein function, and therefore accurate prediction of their structures is...
So far the difficulty to predict the structure of the third hypervariable loop of the heavy chain of...
Antibodies are soluble proteins produced by the adaptive immune system to bind and counteract invadi...
Antibodies are soluble proteins produced by the adaptive immune system to bind and counteract invadi...
'To whom correspondence should be addressed The structure of the most variable antibody hyperva...
Antibodies are proteins that are the recognition elements of the immune system and increasingly used...
Antibodies are an essential part of the immune system. They are able to attain high specificity and...
AbstractFor the third complementarity determining region of the antibody heavy chain (CDR-H3), we pr...
Antibodies are proteins of the adapative immune system. Structural diversity in an antibody's two va...