Clinically approved antidepressants modulate the brain’s emotional valence circuits, suggesting that the response of these circuits could serve as a biomarker for screening candidate antidepressant drugs. Here, we apply a cross-validated predictive model to classify clinical state, emotional valence, and pharmacologic effect across eight task-based fMRI studies (n=306) of the effect of antidepressant administration on emotional face processing
Recent studies have indicated that resting-state functional connectivity (rs-fc) holds great promise...
Background Methods of analysis that examine the pattern of cerebral activity over the whole brain h...
Although most knowledge regarding antidepressant effects is at the receptor level, the neurophysiolo...
Background: Clinically approved antidepressants modulate the brain's emotional valence circuits, sug...
Background. Clinically approved antidepressants modulate the brainâs emotional valence circuits, sug...
BACKGROUND: The neuropharmacological actions of antidepressants are well characterised but our under...
The neurocognitive model of antidepressant treatment action states that antidepressants work by prod...
Antidepressant treatment reduces behavioural and neural markers of negative emotional bias early in ...
Several previous functional magnetic resonance imaging (fMRI) studies have demonstrated the predicti...
Early effects of antidepressants on emotional processing can be seen in healthy volunteers and in de...
Selective serotonin reuptake inhibitors (SSRIs) are effective in the treatment of depression and a r...
The efficacy of antidepressant treatment for depression is controversial due to the only modest supe...
Current antidepressant agents are similar in efficacy to the original drugs discovered in the 1950s....
BACKGROUND: Short-term antidepressant administration has been reported to decrease amygdala response...
Introduction: The prediction of antidepressant treatment response may improve outcome. Functional ma...
Recent studies have indicated that resting-state functional connectivity (rs-fc) holds great promise...
Background Methods of analysis that examine the pattern of cerebral activity over the whole brain h...
Although most knowledge regarding antidepressant effects is at the receptor level, the neurophysiolo...
Background: Clinically approved antidepressants modulate the brain's emotional valence circuits, sug...
Background. Clinically approved antidepressants modulate the brainâs emotional valence circuits, sug...
BACKGROUND: The neuropharmacological actions of antidepressants are well characterised but our under...
The neurocognitive model of antidepressant treatment action states that antidepressants work by prod...
Antidepressant treatment reduces behavioural and neural markers of negative emotional bias early in ...
Several previous functional magnetic resonance imaging (fMRI) studies have demonstrated the predicti...
Early effects of antidepressants on emotional processing can be seen in healthy volunteers and in de...
Selective serotonin reuptake inhibitors (SSRIs) are effective in the treatment of depression and a r...
The efficacy of antidepressant treatment for depression is controversial due to the only modest supe...
Current antidepressant agents are similar in efficacy to the original drugs discovered in the 1950s....
BACKGROUND: Short-term antidepressant administration has been reported to decrease amygdala response...
Introduction: The prediction of antidepressant treatment response may improve outcome. Functional ma...
Recent studies have indicated that resting-state functional connectivity (rs-fc) holds great promise...
Background Methods of analysis that examine the pattern of cerebral activity over the whole brain h...
Although most knowledge regarding antidepressant effects is at the receptor level, the neurophysiolo...