Comparative analysis of algorithms calculating distances of DNA sequences and some related problems

The main focus of this article is to describe our original approach to compare the quality of defined metrics on the set of DNA sequences. The approach is based on the fact, that the triples of distances between genomes should ideally form isosceles acute triangles. On the basis of this assumption, we proposed value of the norm, gives in practice aссeptable results. In the course of work on the implementation of algorithms have been carried out computational experiments with 100 DNA of “distant” species, as well as with representatives of several genomes of great apes and humans.The reported study was funded by RFBR according to the research project № 16-47-630829