Consider finite sequences X[1,n] = X1,...,Xn and Y[1,n] = Y1,...,Yn of length n, consisting of i.i.d. samples of random letters from a finite alphabet, and let S and T be chosen i.i.d. randomly from the unit ball in the space of symmetric scoring functions over this alphabet augmented by a gap symbol. We prove a probabilistic upper bound of linear order in (ln(n))1/4n^3/4 for the deviation of the score relative to T of optimal alignments with gaps of X[1,n] and Y[1,n] relative to S. It remains an open problem to prove a lower bound. Our result contributes to the understanding of the microstructure of optimal alignments relative to one given scoring function, extending a theory begun in (J. Stat. Phys. 153 (2013) 512–529)
MOTIVATION: Sequence alignments obtained using affine gap penalties are not always biologically corr...
The study and comparison of sequences of characters from a finite alphabet is relevant to various ar...
A heuristic approximation to the score distribution of gapped alignments in the logarithmic domain i...
Consider finite sequences $X_{[1,n]}=X_1\dots X_n$ and $Y_{[1,n]}=Y_1\dots Y_n$ of \ud length $n$, c...
Considering optimal alignments of two i.i.d. random sequences of length n, we show that for Lebesgue...
The problem of determining the correct order of fluctuation of the optimal alignment score of two ra...
The problem of determining the correct order of fluctuation of the optimal alignment score of two ra...
We investigate the variance of the optimal alignment score of two independent iid binary, with param...
AbstractWe consider the problem of computing a global alignment between two or more sequences subjec...
We investigate the behavior of optimal alignment paths for related and non-related random sequences....
Abstract. A “semi-probabilistic ” alignment algorithm which combines ideas from Smith-Waterman and p...
The statistical properties of local alignment algorithms with gaps are analyzed theoretically for uu...
We looked at various alignment algorithms with different scoring schemes. We argued that the score o...
A heuristic approximation to the score distribution of gapped alignments in the logarithmic domain i...
International audienceAlignment algorithms usually rely on simplified models of gaps for computation...
MOTIVATION: Sequence alignments obtained using affine gap penalties are not always biologically corr...
The study and comparison of sequences of characters from a finite alphabet is relevant to various ar...
A heuristic approximation to the score distribution of gapped alignments in the logarithmic domain i...
Consider finite sequences $X_{[1,n]}=X_1\dots X_n$ and $Y_{[1,n]}=Y_1\dots Y_n$ of \ud length $n$, c...
Considering optimal alignments of two i.i.d. random sequences of length n, we show that for Lebesgue...
The problem of determining the correct order of fluctuation of the optimal alignment score of two ra...
The problem of determining the correct order of fluctuation of the optimal alignment score of two ra...
We investigate the variance of the optimal alignment score of two independent iid binary, with param...
AbstractWe consider the problem of computing a global alignment between two or more sequences subjec...
We investigate the behavior of optimal alignment paths for related and non-related random sequences....
Abstract. A “semi-probabilistic ” alignment algorithm which combines ideas from Smith-Waterman and p...
The statistical properties of local alignment algorithms with gaps are analyzed theoretically for uu...
We looked at various alignment algorithms with different scoring schemes. We argued that the score o...
A heuristic approximation to the score distribution of gapped alignments in the logarithmic domain i...
International audienceAlignment algorithms usually rely on simplified models of gaps for computation...
MOTIVATION: Sequence alignments obtained using affine gap penalties are not always biologically corr...
The study and comparison of sequences of characters from a finite alphabet is relevant to various ar...
A heuristic approximation to the score distribution of gapped alignments in the logarithmic domain i...