Add to ORKGGlucose is the central nervous system’s only energy source. Imaging techniques capable to detect pathological alterations of the brain metabolism are useful in different diagnostic processes. Such techniques are also beneficial for assessing the evaluation efficacy of therapies in pre-clinical and clinical stages of diseases. Chemical exchange saturation transfer (CEST) magnetic resonance imaging (MRI) is a possible alternative to positron emission tomography (PET) imaging that has been widely explored in cancer research in humans and animal models. We propose that pathological alterations in brain 2-deoxy-D-glucose (2DG) uptake, typical of neurodegenerative diseases, can be detected with CEST MRI. Transgenic mice overexpressing a mutated f...
Abstract. Murine models of Alzheimer’s disease (AD) provide means to detect and follow biomarker cha...
Glucose is the main energy source of cancer cells to proliferate and survive. Recently, promising re...
International audienceBrain glucose uptake was examined in transgenic mice relevant to Alzheimer's d...
Glucose is the central nervous system’s only energy source. Imaging techniques capable to detect pat...
Glucose is the central nervous system's only energy source. Imaging techniques capable to detect pat...
2-Deoxy-D-glucose (2DG) is a known surrogate molecule that is useful for inferring glucose uptake an...
International audienceSince the early eighties MRI has become the most powerful technic for in-vivo ...
International audienceAlzheimer's disease (AD), the most common age-related neurodegenerative disord...
Altered cerebral glucose uptake is one of the hallmarks of Alzheimer's disease (AD). A dynamic gluco...
International audienceBiomarkers and technologies similar to those used in humans are essential for ...
Abstract Neurodegenerative diseases (NDs), such as Alzheimer’s disease (AD), Parkinson’s disease (PD...
Chemical exchange saturation transfer (CEST) magnetic resonance imaging (MRI) detects molecules in t...
Thesis (Ph. D. in Biomedical Engineering)--Harvard-MIT Program in Health Sciences and Technology, 20...
To investigate exchangeable proton signals of Aβ proteins of the brains of Alzheimer's disease ...
Abstract. Murine models of Alzheimer’s disease (AD) provide means to detect and follow biomarker cha...
Glucose is the main energy source of cancer cells to proliferate and survive. Recently, promising re...
International audienceBrain glucose uptake was examined in transgenic mice relevant to Alzheimer's d...
Glucose is the central nervous system’s only energy source. Imaging techniques capable to detect pat...
Glucose is the central nervous system's only energy source. Imaging techniques capable to detect pat...
2-Deoxy-D-glucose (2DG) is a known surrogate molecule that is useful for inferring glucose uptake an...
International audienceSince the early eighties MRI has become the most powerful technic for in-vivo ...
International audienceAlzheimer's disease (AD), the most common age-related neurodegenerative disord...
Altered cerebral glucose uptake is one of the hallmarks of Alzheimer's disease (AD). A dynamic gluco...
International audienceBiomarkers and technologies similar to those used in humans are essential for ...
Abstract Neurodegenerative diseases (NDs), such as Alzheimer’s disease (AD), Parkinson’s disease (PD...
Chemical exchange saturation transfer (CEST) magnetic resonance imaging (MRI) detects molecules in t...
Thesis (Ph. D. in Biomedical Engineering)--Harvard-MIT Program in Health Sciences and Technology, 20...
To investigate exchangeable proton signals of Aβ proteins of the brains of Alzheimer's disease ...
Abstract. Murine models of Alzheimer’s disease (AD) provide means to detect and follow biomarker cha...
Glucose is the main energy source of cancer cells to proliferate and survive. Recently, promising re...
International audienceBrain glucose uptake was examined in transgenic mice relevant to Alzheimer's d...