The first cell fate choice in mouse development is the segregation of the embryonic inner cell mass and the extra-embryonic trophectoderm. In this issue of Developmental Cell, Korotkevic and colleagues (2017) show that the interplay between cell polarization and cell-cell contact drives the segregation of these lineages, providing a framework for self-organization in development
Cleavage is a period after fertilization, when a 1-cell embryo starts developing into a multicellula...
Background: During mammalian preimplantation development, lineage divergence seems to be controlled ...
Polarity formation in mammalian preimplantation embryos has long been a subject of controversy. Mamm...
The first cell fate choice in mouse development is the segregation of the embryonic inner cell mass ...
Cell polarization is critical for lineage segregation and morphogenesis during mammalian embryogenes...
The separation of inner cell mass and trophectoderm is the first cell fate specification event in ma...
Although the mechanisms underlying the divergence of the first cell types in the mouse, the trophect...
Establishing polarity is a fundamental part of embryogenesis and can be traced back to the earliest ...
Mammalian development begins with segregation of the extra-embryonic trophectoderm from the embryoni...
The formation of trophectoderm (TE) and pluripotent inner cell mass (ICM) is one of the earliest eve...
Early development of the mouse comprises a sequence of cell fate decisions in which cells are guided...
Specification of cell fate in the early mouse embryo involves the generation of heterogeneities betw...
A crucial question in mammalian development is how cells of the early embryo differentiate into dist...
International audienceBACKGROUND: During mammalian preimplantation development, lineage divergence s...
The formation of trophectoderm (TE) and pluripotent inner cell mass (ICM) is one of the earliest eve...
Cleavage is a period after fertilization, when a 1-cell embryo starts developing into a multicellula...
Background: During mammalian preimplantation development, lineage divergence seems to be controlled ...
Polarity formation in mammalian preimplantation embryos has long been a subject of controversy. Mamm...
The first cell fate choice in mouse development is the segregation of the embryonic inner cell mass ...
Cell polarization is critical for lineage segregation and morphogenesis during mammalian embryogenes...
The separation of inner cell mass and trophectoderm is the first cell fate specification event in ma...
Although the mechanisms underlying the divergence of the first cell types in the mouse, the trophect...
Establishing polarity is a fundamental part of embryogenesis and can be traced back to the earliest ...
Mammalian development begins with segregation of the extra-embryonic trophectoderm from the embryoni...
The formation of trophectoderm (TE) and pluripotent inner cell mass (ICM) is one of the earliest eve...
Early development of the mouse comprises a sequence of cell fate decisions in which cells are guided...
Specification of cell fate in the early mouse embryo involves the generation of heterogeneities betw...
A crucial question in mammalian development is how cells of the early embryo differentiate into dist...
International audienceBACKGROUND: During mammalian preimplantation development, lineage divergence s...
The formation of trophectoderm (TE) and pluripotent inner cell mass (ICM) is one of the earliest eve...
Cleavage is a period after fertilization, when a 1-cell embryo starts developing into a multicellula...
Background: During mammalian preimplantation development, lineage divergence seems to be controlled ...
Polarity formation in mammalian preimplantation embryos has long been a subject of controversy. Mamm...