Plant Extracts and Efflux Pump Inhibition

Bacterial infection is now, more than ever, a major health concern for people everywhere. Bacterial resistance is widespread and continually growing, which calls for an innovative technique to the traditional approach of developing new antibiotics. One of bacteria’s quickest and most effective mechanisms to develop antibiotic resistance is through multi-drug resistant efflux pumps. Using natural plant sources, extracts have been tested against bacterial strains of Escherichia coli. Two main tests have been conducted in order to determine effectiveness of each plant extract. Ultimately, the goal of this project has been to find novel approaches to assist in the ongoing fight against resistant bacterial strains