Add to ORKGAutoimmune regulator (Aire) promotes the ectopic expression of tissue-restricted antigens in medullary thymic epithelial cells (mTECs), leading to negative selection of autoreactive T cells. This study was undertaken to determine whether loss of central tolerance renders Aire-deficient (Aire-/-) mice more susceptible to the induction of autoimmune arthritis.status: publishe
Developing T cells encounter peripheral self-antigens in the thymus in order to delete autoreactive ...
Autoimmune regulator (AIRE), whose gene mutation is considered to be a causative factor of autoimmun...
Developing T cells encounter peripheral self-antigens in the thymus in order to delete autoreactive ...
ObjectiveAutoimmune regulator (Aire) promotes the ectopic expression of tissue-restricted antigens i...
The maintenance of immune tolerance is an essential process to prevent autoimmunity. A critical prot...
Autoimmunity is prevented by the function of the autoimmune regulator [AIRE (Aire in mice)], which p...
The autoimmune regulator (Aire) was initially identified as the gene causing multiorgan system autoi...
<p>As a transcription factor, autoimmune regulator (Aire) participates in thymic negative selection ...
The autoimmune regulator (AIRE) is a facilitator of gene transcription found primarily in the thymus...
AbstractMutations in the Autoimmune Regulator (AIRE) gene are responsible for Autoimmune Polyendocri...
Mutations of the Autoimmune Regulator (Aire) were first identified as the cause of a multi-organ aut...
The mechanism underlying the generation of T and B autoreactive clones in autoimmune diseases is sti...
The aim of the work presented in this thesis was to investigate how failure in the mechanisms that r...
Developing T cells encounter peripheral self-antigens in the thymus in order to delete autoreactive ...
Mutations in the autoimmune regulator (AIRE) gene lead to autoimmune polyendocrinopathy syndrome typ...
Developing T cells encounter peripheral self-antigens in the thymus in order to delete autoreactive ...
Autoimmune regulator (AIRE), whose gene mutation is considered to be a causative factor of autoimmun...
Developing T cells encounter peripheral self-antigens in the thymus in order to delete autoreactive ...
ObjectiveAutoimmune regulator (Aire) promotes the ectopic expression of tissue-restricted antigens i...
The maintenance of immune tolerance is an essential process to prevent autoimmunity. A critical prot...
Autoimmunity is prevented by the function of the autoimmune regulator [AIRE (Aire in mice)], which p...
The autoimmune regulator (Aire) was initially identified as the gene causing multiorgan system autoi...
<p>As a transcription factor, autoimmune regulator (Aire) participates in thymic negative selection ...
The autoimmune regulator (AIRE) is a facilitator of gene transcription found primarily in the thymus...
AbstractMutations in the Autoimmune Regulator (AIRE) gene are responsible for Autoimmune Polyendocri...
Mutations of the Autoimmune Regulator (Aire) were first identified as the cause of a multi-organ aut...
The mechanism underlying the generation of T and B autoreactive clones in autoimmune diseases is sti...
The aim of the work presented in this thesis was to investigate how failure in the mechanisms that r...
Developing T cells encounter peripheral self-antigens in the thymus in order to delete autoreactive ...
Mutations in the autoimmune regulator (AIRE) gene lead to autoimmune polyendocrinopathy syndrome typ...
Developing T cells encounter peripheral self-antigens in the thymus in order to delete autoreactive ...
Autoimmune regulator (AIRE), whose gene mutation is considered to be a causative factor of autoimmun...
Developing T cells encounter peripheral self-antigens in the thymus in order to delete autoreactive ...