Genetic markers of bevacizumab-induced hypertension
- Lambrechts, Diether
- Moisse, Matthieu
- Delmar, Paul
- Miles, David W
- Leighl, Natasha
- Escudier, Bernard
- Van Cutsem, Eric
- Bansal, Aruna T
- Carmeliet, Peter
- Scherer, Stefan J
- de Haas, Sanne
- Pallaud, Celine
Publication date
July 2014
DOI Publisher
Rapid Science Publishers ISSN
0969-6970 Journal
issn:0969-6970 Citation count (estimate)
14Abstract
There are currently no validated biomarkers predicting bevacizumab treatment outcome or toxicity. We combined biomarker data from six phase III trials of bevacizumab to assess whether genetic variation in vascular endothelial growth factor-A (VEGF-A) pathway or hypertension-related genes are associated with bevacizumab-induced hypertension.status: publishe
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