In 2008, 25 years after the human immunodeficiency virus (HIV) was discovered as the then tentative aetiological agent of acquired immune deficiency syndrome (AIDS), exactly 25 anti-HIV compounds have been formally approved for clinical use in the treatment of AIDS. These compounds fall into six categories: nucleoside reverse transcriptase inhibitors (NRTIs: zidovudine, didanosine, zalcitabine, stavudine, lamivudine, abacavir and emtricitabine); nucleotide reverse transcriptase inhibitors (NtRTIs: tenofovir); non-nucleoside reverse transcriptase inhibitors (NNRTIs: nevirapine, delavirdine, efavirenz and etravirine); protease inhibitors (PIs: saquinavir, ritonavir, indinavir, nelfinavir, amprenavir, lopinavir, atazanavir, fosamprenavir, tipr...
Fifty years of research (1968-2018) toward the identification of selective antiviral drugs have been...
HIV fusion and entry are two steps in the viral lifecycle that can be targeted by several classes of...
AIDS is not a virus but a set of symptoms caused by the HIV virus. A person is said to have AIDS whe...
Within 25 years after zidovudine (3'-azido-2',3'-dideoxythymidine, AZT) was first described as an in...
There are, at present, 22 compounds which have been formally approved (by the US Food and Drug Admin...
In October 2010, it will be exactly 25 years ago that the first antiretroviral drug, AZT (zidovudine...
Human immunodeficiency virus type 1 (HIV-1) is the causative agent of acquired immunodeficiency dise...
There are at present exactly 25 compounds that have been formally approved for the treatment of retr...
Antiviral therapy directed against human immu-nodeficiency virus type 1 (HIV-1) is now ap-proaching ...
AbstractDespite the availability of 16 antiretroviral drugs approved for the treatment of HIV infect...
Of the multitude of reverse transcriptase inhibitors and protease inhibitors that have been pursued ...
Since 1987 major advances have been made in our understanding of the patho-genesis of infection and ...
Currently available anti-HIV drugs can be classified into three categories: nucleoside analogue reve...
The majority of the drugs currently used for the treatment of HIV infections (AIDS) belong to either...
The majority of the drugs currently used for the treatment of HIV infections (AIDS) belong to either...
Fifty years of research (1968-2018) toward the identification of selective antiviral drugs have been...
HIV fusion and entry are two steps in the viral lifecycle that can be targeted by several classes of...
AIDS is not a virus but a set of symptoms caused by the HIV virus. A person is said to have AIDS whe...
Within 25 years after zidovudine (3'-azido-2',3'-dideoxythymidine, AZT) was first described as an in...
There are, at present, 22 compounds which have been formally approved (by the US Food and Drug Admin...
In October 2010, it will be exactly 25 years ago that the first antiretroviral drug, AZT (zidovudine...
Human immunodeficiency virus type 1 (HIV-1) is the causative agent of acquired immunodeficiency dise...
There are at present exactly 25 compounds that have been formally approved for the treatment of retr...
Antiviral therapy directed against human immu-nodeficiency virus type 1 (HIV-1) is now ap-proaching ...
AbstractDespite the availability of 16 antiretroviral drugs approved for the treatment of HIV infect...
Of the multitude of reverse transcriptase inhibitors and protease inhibitors that have been pursued ...
Since 1987 major advances have been made in our understanding of the patho-genesis of infection and ...
Currently available anti-HIV drugs can be classified into three categories: nucleoside analogue reve...
The majority of the drugs currently used for the treatment of HIV infections (AIDS) belong to either...
The majority of the drugs currently used for the treatment of HIV infections (AIDS) belong to either...
Fifty years of research (1968-2018) toward the identification of selective antiviral drugs have been...
HIV fusion and entry are two steps in the viral lifecycle that can be targeted by several classes of...
AIDS is not a virus but a set of symptoms caused by the HIV virus. A person is said to have AIDS whe...