Structure and Evolution of prokaryotic transcription factor binding sites

With the ever-increasing number of available sequenced bacterial genomes and the availability of high throughput experimental approaches such as chromatine immuno-precipitation sequencing (ChIP-seq), it has become possible to extend our knowledge about the transcriptional regulation from model organisms to other bacteria. Recent research has focused especially on the comparison of closely related species, allowing us to get insight into the different regulatory evolutionary events creating phenotypic diversity and involved in the evolution of bacterial gene regulatory networks.status: publishe