The long-term goal of this project is to chemically synthesize an unnatural fluorescent amino acid, 3-[7-nitro-2,1,3-benzoxadiazol-4-yl]-L-alanine. This amino acid can be used to build glow-in-the-dark proteins, allowing investigators to visualize a single protein in an otherwise transparent living cell. We have been unable to replicate the previously reported synthesis and are exploring different reaction conditions and workup procedures. To determine the efficiency of the new reaction conditions, reaction kinetics will be analyzed using 1H-NMR and LCMS, which follow the reactions over time
Reported here is the direct synthesis and application of unnatural amino acids for the development o...
An unnatural amino acid, azalysine, was synthesized using several proposed procedures with the gener...
Synthesis of fluorescent derivatives of lysine fluorescent probes: 4-phenylspiro[furan-2(3.I.H./I.),...
The long-term goal of this project is to chemically synthesize an unnatural fluorescent amino acid (...
The long-term goal of this project is to develop a more cost-effective chemical synthesis of an unna...
The goal of this project is to chemically synthesize a fluorescent amino acid that will later be use...
Unnatural fluorescent amino acids are important tools that allow biochemists to visualize proteins i...
Unnatural fluorescent amino acids are important tools that allow biochemists to visualize proteins i...
Unnatural fluorescent amino acids are important tools that allow biochemists to visualize proteins i...
The long-term goal of this project is to chemically synthesize an unnatural fluorescent amino acid (...
The long-term goal of this project is to chemically synthesize an unnatural fluorescent amino acid, ...
The long-term goal of this project is to more efficiently synthesize an unnatural fluorescent amino ...
The goal of this project is to chemically synthesize a fluorescent amino acid that will later be use...
In the past decade, fluorescent proteins (FPs), such as GFP, have revolutionized the study of micros...
New fluorescent amino acids bearing pyrenyl groups were synthesized and their photophysical properti...
Reported here is the direct synthesis and application of unnatural amino acids for the development o...
An unnatural amino acid, azalysine, was synthesized using several proposed procedures with the gener...
Synthesis of fluorescent derivatives of lysine fluorescent probes: 4-phenylspiro[furan-2(3.I.H./I.),...
The long-term goal of this project is to chemically synthesize an unnatural fluorescent amino acid (...
The long-term goal of this project is to develop a more cost-effective chemical synthesis of an unna...
The goal of this project is to chemically synthesize a fluorescent amino acid that will later be use...
Unnatural fluorescent amino acids are important tools that allow biochemists to visualize proteins i...
Unnatural fluorescent amino acids are important tools that allow biochemists to visualize proteins i...
Unnatural fluorescent amino acids are important tools that allow biochemists to visualize proteins i...
The long-term goal of this project is to chemically synthesize an unnatural fluorescent amino acid (...
The long-term goal of this project is to chemically synthesize an unnatural fluorescent amino acid, ...
The long-term goal of this project is to more efficiently synthesize an unnatural fluorescent amino ...
The goal of this project is to chemically synthesize a fluorescent amino acid that will later be use...
In the past decade, fluorescent proteins (FPs), such as GFP, have revolutionized the study of micros...
New fluorescent amino acids bearing pyrenyl groups were synthesized and their photophysical properti...
Reported here is the direct synthesis and application of unnatural amino acids for the development o...
An unnatural amino acid, azalysine, was synthesized using several proposed procedures with the gener...
Synthesis of fluorescent derivatives of lysine fluorescent probes: 4-phenylspiro[furan-2(3.I.H./I.),...