CD4+ T cells -- often referred to as T-helper cells -- play a central role in immune defense and pathogenesis. Virus infections and vaccines stimulate and expand populations of antigen-specific CD4+ T cells in mice and in man. These virus-specific CD4+ T cells are extremely important in antiviral protection: deficiencies in CD4+ T cells are associated with virus reactivation, generalized susceptibility to opportunistic infections, and poor vaccine efficacy. As described below, CD4+ T cells influence effector and memory CD8+ T cell responses, humoral immunity, and the antimicrobial activity of macrophages and are involved in recruiting cells to sites of infection. This review summarizes a few key points about the dynamics of the CD4+ T cell ...
Summary: We have outlined the carefully orchestrated process of CD4<sup>+</sup> T-cell differentiati...
Vertebrates are constantly exposed to pathogens, and the adaptive immunity has most likely evolved t...
T follicular helper (TFH) and Cytotoxic CD4 (ThCTL) are tissue-restricted CD4 effector subsets, func...
CD4+ T cells -- often referred to as T-helper cells -- play a central role in immune defense and pat...
CD4+ T cells -- often referred to as T-helper cells -- play a central role in immune defense and pat...
CD4+ T cells -- often referred to as T-helper cells -- play a central role in immune defense and pat...
AbstractCD4+ T cells – often referred to as T-helper cells – play a central role in immune defense a...
AbstractCD4+ T cells – often referred to as T-helper cells – play a central role in immune defense a...
CD4 T cells that acquire cytotoxic phenotype and function have been repeatedly identified in humans,...
Immunological memory provides rapid protection to pathogens previously encountered through infection...
<p>The role of CD4 T cell help in primary and secondary CD8 T cell responses to infectious pathogens...
The goal of this body of research was to elucidate the mechanism by which CD4+ T cells provide help ...
T cell protective immunity is associated with multifunctional memory cells that produce several diff...
T cell protective immunity is associated with multifunctional memory cells that produce several diff...
The processes that regulate viral vector vaccine-elicited cellular and humoral immune responses rema...
Summary: We have outlined the carefully orchestrated process of CD4<sup>+</sup> T-cell differentiati...
Vertebrates are constantly exposed to pathogens, and the adaptive immunity has most likely evolved t...
T follicular helper (TFH) and Cytotoxic CD4 (ThCTL) are tissue-restricted CD4 effector subsets, func...
CD4+ T cells -- often referred to as T-helper cells -- play a central role in immune defense and pat...
CD4+ T cells -- often referred to as T-helper cells -- play a central role in immune defense and pat...
CD4+ T cells -- often referred to as T-helper cells -- play a central role in immune defense and pat...
AbstractCD4+ T cells – often referred to as T-helper cells – play a central role in immune defense a...
AbstractCD4+ T cells – often referred to as T-helper cells – play a central role in immune defense a...
CD4 T cells that acquire cytotoxic phenotype and function have been repeatedly identified in humans,...
Immunological memory provides rapid protection to pathogens previously encountered through infection...
<p>The role of CD4 T cell help in primary and secondary CD8 T cell responses to infectious pathogens...
The goal of this body of research was to elucidate the mechanism by which CD4+ T cells provide help ...
T cell protective immunity is associated with multifunctional memory cells that produce several diff...
T cell protective immunity is associated with multifunctional memory cells that produce several diff...
The processes that regulate viral vector vaccine-elicited cellular and humoral immune responses rema...
Summary: We have outlined the carefully orchestrated process of CD4<sup>+</sup> T-cell differentiati...
Vertebrates are constantly exposed to pathogens, and the adaptive immunity has most likely evolved t...
T follicular helper (TFH) and Cytotoxic CD4 (ThCTL) are tissue-restricted CD4 effector subsets, func...