Effects of folic acid supplementation on overall and site-specific cancer incidence during the randomised trials: meta-analyses of data on 50 000 individuals
- Vollset, Stein Emil
- Clarke, Robert
- Lewington, Sarah
- Ebbing, Marta
- Halsey, Jim
- Lonn, Eva
- Armitage, Jane
- Manson, JoAnn E
- Hankey, Graeme J
- Spence, J David
- Galan, Pilar
- Bønaa, Kaare H
- Jamison, Rex
- Gaziano, J Michael
- Guarino, Peter
- Baron, John A
- Logan, Richard FA
- Giovannucci, Edward L
- den Heijer, Martin
- Ueland, Per M
- Bennett, Derrick
- Collins, Rory
- Peto, Richard
Publication date
January 2013
DOIAbstract
Some countries fortify flour with folic acid to prevent neural tube defects but others do not, partly because of concerns about cancer risks. We aimed to assess the effects of folic acid supplementation on site-specific cancer rates in the randomised trials
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