This study characterized 99mTc-Mebrofenin (MEB) and 99mTc-Sestamibi (MIBI) hepatic transport and preferential efflux routes (canalicular vs. basolateral) in rat and human sandwich-cultured hepatocytes (SCH)
Transport proteins in the liver play a crucial role in hepatic uptake and biliary excretion of drugs...
The objective of this dissertation project was to develop preclinical and clinical tools to assess t...
The objectives of this research were to investigate mechanisms of drug-induced liver injury (DILI) t...
This study characterized 99mTc-Mebrofenin (MEB) and 99mTc-Sestamibi (MIBI) hepatic transport and pre...
The objective of this research project was to identify and characterize probe substrates for specifi...
Transport of the hepatobiliary scintigraphy agent Tc-99m mebrofenin (MEB) was characterized, and sim...
International audienceThe multidrug resistance-associated protein 2 (MRP2) mediates the biliary excr...
The objective of this research project was to develop preclinical and clinical tools to assess hepat...
Multidrug resistance associated proteins (MRPs) and P-glycoprotein (P-gp) are involved in hepatobili...
Background & Aims: (99m)Tc-mebrofenin hepatobiliary scintigraphy (HBS) and the indocyanine green (IC...
International audienceEndotoxemia-induced inflammation may impact the activity of hepatocyte transpo...
Hepatic transport of Tc-99m-mebrofenin through organic anion transport protein 1a and 1b (Oatp1a/1b)...
Many diseases are associated with cytokine release after in-flammatory infiltration, which perturbs ...
The objective of this doctoral dissertation research was to understand how hepatic transporter funct...
Hepatobiliary imaging is increasingly used by pharmacologists to quantify liver concentrations of tr...
Transport proteins in the liver play a crucial role in hepatic uptake and biliary excretion of drugs...
The objective of this dissertation project was to develop preclinical and clinical tools to assess t...
The objectives of this research were to investigate mechanisms of drug-induced liver injury (DILI) t...
This study characterized 99mTc-Mebrofenin (MEB) and 99mTc-Sestamibi (MIBI) hepatic transport and pre...
The objective of this research project was to identify and characterize probe substrates for specifi...
Transport of the hepatobiliary scintigraphy agent Tc-99m mebrofenin (MEB) was characterized, and sim...
International audienceThe multidrug resistance-associated protein 2 (MRP2) mediates the biliary excr...
The objective of this research project was to develop preclinical and clinical tools to assess hepat...
Multidrug resistance associated proteins (MRPs) and P-glycoprotein (P-gp) are involved in hepatobili...
Background & Aims: (99m)Tc-mebrofenin hepatobiliary scintigraphy (HBS) and the indocyanine green (IC...
International audienceEndotoxemia-induced inflammation may impact the activity of hepatocyte transpo...
Hepatic transport of Tc-99m-mebrofenin through organic anion transport protein 1a and 1b (Oatp1a/1b)...
Many diseases are associated with cytokine release after in-flammatory infiltration, which perturbs ...
The objective of this doctoral dissertation research was to understand how hepatic transporter funct...
Hepatobiliary imaging is increasingly used by pharmacologists to quantify liver concentrations of tr...
Transport proteins in the liver play a crucial role in hepatic uptake and biliary excretion of drugs...
The objective of this dissertation project was to develop preclinical and clinical tools to assess t...
The objectives of this research were to investigate mechanisms of drug-induced liver injury (DILI) t...
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