The enantioselective synthesis of FD-891 has been achieved with a longest linear sequence of 21 steps. The synthetic strategy involves the use of aldol additions of a chlorotitanium enolate of N-acylthiazolidinethiones as the key reaction to establish 6 of the 10 stereogenic centers. A key cross-metathesis and a late-stage Julia olefination serve to assemble three key subunits
A concise and unified strategy for the synthesis of C1–C18 macrolactone fragments of FD-891 and FD-8...
The diastereoselective synthesis of b-hydroxy ketones via quaternary Claisen condensation is describ...
The thesis entitled “Total synthesis of bio-active macrolide natural products and sulphonamide based...
The enantioselective synthesis of FD-891 has been achieved with a longest linear sequence of 21 step...
The enantioselective synthesis of bistramide A has been achieved with a longest linear sequence of 1...
Synthesis of the C1-C6 and C7-C23 fragments of the proposed structure of iriomoteolide 1a has been a...
The enantioselective total synthesis of spirofungins A (1) and B (2) is reported in 14 steps over th...
A highly stereocontrolled total synthesis of the 18-membered macrolide (+)-concanamycin F, a potent ...
Enediyne antitumor antibiotics have attracted immense attention among chemists and biologists alike ...
A proposed strategy for the enantioselective total synthesis of luminacin D, one of a family of 14 s...
A highly convergent, enantioselective total synthesis of the potent antitumor agent apoptolidin A, h...
The benzolactone enamide natural products are identified by three structural characteristics: a sali...
The total synthesis of FD-895 was completed through a strategy that featured the use of a tandem est...
Graduation date: 2016Access restricted to the OSU Community, at author's request, from November 24, ...
Anti-selective aldol additions between the titanium enolates of N-glycolyl oxazolidinethiones and si...
A concise and unified strategy for the synthesis of C1–C18 macrolactone fragments of FD-891 and FD-8...
The diastereoselective synthesis of b-hydroxy ketones via quaternary Claisen condensation is describ...
The thesis entitled “Total synthesis of bio-active macrolide natural products and sulphonamide based...
The enantioselective synthesis of FD-891 has been achieved with a longest linear sequence of 21 step...
The enantioselective synthesis of bistramide A has been achieved with a longest linear sequence of 1...
Synthesis of the C1-C6 and C7-C23 fragments of the proposed structure of iriomoteolide 1a has been a...
The enantioselective total synthesis of spirofungins A (1) and B (2) is reported in 14 steps over th...
A highly stereocontrolled total synthesis of the 18-membered macrolide (+)-concanamycin F, a potent ...
Enediyne antitumor antibiotics have attracted immense attention among chemists and biologists alike ...
A proposed strategy for the enantioselective total synthesis of luminacin D, one of a family of 14 s...
A highly convergent, enantioselective total synthesis of the potent antitumor agent apoptolidin A, h...
The benzolactone enamide natural products are identified by three structural characteristics: a sali...
The total synthesis of FD-895 was completed through a strategy that featured the use of a tandem est...
Graduation date: 2016Access restricted to the OSU Community, at author's request, from November 24, ...
Anti-selective aldol additions between the titanium enolates of N-glycolyl oxazolidinethiones and si...
A concise and unified strategy for the synthesis of C1–C18 macrolactone fragments of FD-891 and FD-8...
The diastereoselective synthesis of b-hydroxy ketones via quaternary Claisen condensation is describ...
The thesis entitled “Total synthesis of bio-active macrolide natural products and sulphonamide based...
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