A cognitive decline precedes the onset of psychosis in patients with the 22q11.2 deletion syndrome
- Vorstman, Jacob A. S.
- Breetvelt, Elemi J.
- Duijff, Sasja N.
- Eliez, Stephan
- Schneider, Maude
- Jalbrzikowski, Maria
- Armando, Marco
- Vicari, Stefano
- Shashi, Vandana
- Hooper, Stephen R.
- Chow, Eva W. C.
- Fung, Wai Lun Alan
- Butcher, Nancy J.
- Young, Donald A.
- McDonald-McGinn, Donna M.
- Vogels, Annick
- van Amelsvoort, Therese
- Gothelf, Doron
- Weinberger, Ronnie
- Weizman, Abraham
- Klaassen, Petra W. J.
- Koops, Sanne
- Kates, Wendy R.
- Antshel, Kevin M.
- Simon, Tony J.
- Ousley, Opal Y.
- Swillen, Ann
- Gur, Raquel E.
- Bearden, Carrie E.
- Kahn, René S.
- Bassett, Anne S.
Publication date
January 2015
DOIAbstract
Patients with 22q11.2 deletion syndrome (22q11DS) have an elevated (25%) risk for developing schizophrenia. Recent reports have suggested that a subgroup of children with 22q11DS display a substantial decline in cognitive abilities, starting at a young age
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