Chloride Channel ClC-2 is a Key Factor in the Development of DSS-induced Murine Colitis:

Desmoglein2 Regulates Claudin2 Expression by Sequestering PI-3-Kinase in Intestinal Epithelial Cells

Burkard, Natalie
Meir, Michael
Kannapin, Felix
Otto, Christoph
Petzke, Maximilian
Germer, Christoph-Thomas
Waschke, Jens
Schlegel, Nicolas

January 2021

Inflammation-induced reduction of intestinal desmosomal cadherin Desmoglein 2 (Dsg2) is linked to ch...

Desmoglein2 Regulates Claudin2 Expression by Sequestering PI-3-Kinase in Intestinal Epithelial Cells

Burkard, Natalie
Meir, Michael
Kannapin, Felix
Otto, Christoph
Petzke, Maximilian
Germer, Christoph-Thomas
Waschke, Jens
Schlegel, Nicolas

January 2021

Inflammation-induced reduction of intestinal desmosomal cadherin Desmoglein 2 (Dsg2) is linked to ch...

Microbial products induce claudin-2 to compromise gut epithelial barrier function.

Xiaoyu Liu
Gui Yang
Xiao-Rui Geng
Yanjuan Cao
Na Li
Li Ma
Si Chen
Ping-Chang Yang
Zhigang Liu

The epithelial barrier dysfunction is an important pathogenic feature in a number of diseases. The u...

Chloride Channel ClC-2 is a Key Factor in the Development of DSS-induced Murine Colitis:

Nighot, Prashant
Young, Karen
Nighot, Meghali
Rawat, Manmeet
Sung, Eui J.
Maharshak, Nitsan
Plevy, Scott E.
Ma, Thomas
Blikslager, Anthony

January 2013

Previously, we have shown that the chloride channel ClC-2 modulates intestinal tight junction (TJ) b...

The role of ClC-2 in intestinal chloride secretion

Gyomorey, Katalin

January 2000

grantor: University of TorontoCystic Fibrosis (CF) is caused by mutations in the Cystic Fi...

The role of ClC-2 in intestinal chloride secretion

Gyomorey, Katalin

January 2000

grantor: University of TorontoCystic Fibrosis (CF) is caused by mutations in the Cystic Fi...

Intestinal epithelial cell-specific deletion of PLD2 alleviates DSS-induced colitis by regulating occludin

Chelakkot, C.
Ghim, J.
Rajasekaran, N.
Choi, J.-S.
Kim, J.-H.
Jang, M.H.
Shin, Y.K.
Suh, P.-G.
Ryu, S.H.

February 2019

Ulcerative colitis is a multi-factorial disease involving a dysregulated immune response. Disruption...

Intestinal Epithelial Cell-Specific Deletion of PLD2 Alleviates DSS-Induced Colitis by Regulating Occludin

Chelakkot, Chaithanya
Ghim, Jaewang
Rajasekaran, Nirmal
Choi, Jong-Sun
Kim, Jung-Hwan
Jang, Myoung Ho
Shin, Young Kee
Suh, Pann-Ghill
Ryu, Sung Ho

May 2017

Ulcerative colitis is a multi-factorial disease involving a dysregulated immune response. Disruption...

Mechanisms regulating intestinal barrier integrity and its pathological implications

CHAITHANYA, LAKSHMI CHELAKKOT GOVINDALAYA
Ghim, Jaewang
Ryu, Sung Ho

August 2018

The gastrointestinal tract is a specialized organ in which dynamic interactions between host cells a...

CDT of <i>Clostridioides difficile</i> Induces MLC-Dependent Intestinal Barrier Dysfunction in HT-29/B6 Epithelial Cell Monolayers

Lucas Heils
Martina Schneemann
Ralf Gerhard
Jörg-Dieter Schulzke
Roland Bücker

January 2023

Background: Clostridioides difficile binary toxin (CDT) defines the hypervirulence of strains in nos...

Blikslager. Recovery of Mucosal Barrier Function in Ischemic Porcine Ileum and Colon

Adam J. Moeser
Prashant K Nighot
Kory J. Engelke
Anthony T. Blikslager
Moeser Adam J
Prashant K. Nighot
Kory J. Engelke
Ryuji Ueno
Anthony T

October 2016

is Stimulated by a Novel Agonist of the ClC-2 Chloride Channel, Lubiprostone-Previous studies utiliz...

Molecular Investigation of the Intestinal Barrier in Health and Disease

Ebangwese, Santita

May 2019

The intestinal epithelial barrier contributes to the absorption of nutrients and in maintaining home...

Role of goblet cell protein CLCA1 in murine DSS colitis

Erickson, Nancy A.
Mundhenk, Lars
Giovannini, Samoa
Glauben, Rainer
Heimesaat, Markus M.
Gruber, Achim D.

January 2016

Background The secreted goblet cell protein CLCA1 (chloride channel regulator, calcium-activated-1) ...

Desmoglein2 Regulates Claudin2 Expression by Sequestering PI-3-Kinase in Intestinal Epithelial Cells

Burkard, Natalie
Meir, Michael
Kannapin, Felix
Otto, Christoph
Petzke, Maximilian
Germer, Christoph-Thomas
Waschke, Jens
Schlegel, Nicolas

January 2021

Inflammation-induced reduction of intestinal desmosomal cadherin Desmoglein 2 (Dsg2) is linked to ch...

Desmoglein2 Regulates Claudin2 Expression by Sequestering PI-3-Kinase in Intestinal Epithelial Cells

Natalie Burkard
Michael Meir
Felix Kannapin
Christoph Otto
Maximilian Petzke
Christoph-Thomas Germer
Jens Waschke
Nicolas Schlegel

September 2021

Inflammation-induced reduction of intestinal desmosomal cadherin Desmoglein 2 (Dsg2) is linked to ch...

Desmoglein2 Regulates Claudin2 Expression by Sequestering PI-3-Kinase in Intestinal Epithelial Cells

Burkard, Natalie
Meir, Michael
Kannapin, Felix
Otto, Christoph
Petzke, Maximilian
Germer, Christoph-Thomas
Waschke, Jens
Schlegel, Nicolas

January 2021

Inflammation-induced reduction of intestinal desmosomal cadherin Desmoglein 2 (Dsg2) is linked to ch...

Desmoglein2 Regulates Claudin2 Expression by Sequestering PI-3-Kinase in Intestinal Epithelial Cells

Burkard, Natalie
Meir, Michael
Kannapin, Felix
Otto, Christoph
Petzke, Maximilian
Germer, Christoph-Thomas
Waschke, Jens
Schlegel, Nicolas

January 2021

Inflammation-induced reduction of intestinal desmosomal cadherin Desmoglein 2 (Dsg2) is linked to ch...

Microbial products induce claudin-2 to compromise gut epithelial barrier function.

Xiaoyu Liu
Gui Yang
Xiao-Rui Geng
Yanjuan Cao
Na Li
Li Ma
Si Chen
Ping-Chang Yang
Zhigang Liu

The epithelial barrier dysfunction is an important pathogenic feature in a number of diseases. The u...

Chloride Channel ClC-2 is a Key Factor in the Development of DSS-induced Murine Colitis:

Nighot, Prashant
Young, Karen
Nighot, Meghali
Rawat, Manmeet
Sung, Eui J.
Maharshak, Nitsan
Plevy, Scott E.
Ma, Thomas
Blikslager, Anthony

January 2013

Previously, we have shown that the chloride channel ClC-2 modulates intestinal tight junction (TJ) b...

The role of ClC-2 in intestinal chloride secretion

Gyomorey, Katalin

January 2000

grantor: University of TorontoCystic Fibrosis (CF) is caused by mutations in the Cystic Fi...

The role of ClC-2 in intestinal chloride secretion

Gyomorey, Katalin

January 2000

grantor: University of TorontoCystic Fibrosis (CF) is caused by mutations in the Cystic Fi...

Intestinal epithelial cell-specific deletion of PLD2 alleviates DSS-induced colitis by regulating occludin

Chelakkot, C.
Ghim, J.
Rajasekaran, N.
Choi, J.-S.
Kim, J.-H.
Jang, M.H.
Shin, Y.K.
Suh, P.-G.
Ryu, S.H.

February 2019

Ulcerative colitis is a multi-factorial disease involving a dysregulated immune response. Disruption...

Intestinal Epithelial Cell-Specific Deletion of PLD2 Alleviates DSS-Induced Colitis by Regulating Occludin

Chelakkot, Chaithanya
Ghim, Jaewang
Rajasekaran, Nirmal
Choi, Jong-Sun
Kim, Jung-Hwan
Jang, Myoung Ho
Shin, Young Kee
Suh, Pann-Ghill
Ryu, Sung Ho

May 2017

Ulcerative colitis is a multi-factorial disease involving a dysregulated immune response. Disruption...

Mechanisms regulating intestinal barrier integrity and its pathological implications

CHAITHANYA, LAKSHMI CHELAKKOT GOVINDALAYA
Ghim, Jaewang
Ryu, Sung Ho

August 2018

The gastrointestinal tract is a specialized organ in which dynamic interactions between host cells a...

CDT of <i>Clostridioides difficile</i> Induces MLC-Dependent Intestinal Barrier Dysfunction in HT-29/B6 Epithelial Cell Monolayers

Lucas Heils
Martina Schneemann
Ralf Gerhard
Jörg-Dieter Schulzke
Roland Bücker

January 2023

Background: Clostridioides difficile binary toxin (CDT) defines the hypervirulence of strains in nos...

Blikslager. Recovery of Mucosal Barrier Function in Ischemic Porcine Ileum and Colon

Adam J. Moeser
Prashant K Nighot
Kory J. Engelke
Anthony T. Blikslager
Moeser Adam J
Prashant K. Nighot
Kory J. Engelke
Ryuji Ueno
Anthony T

October 2016

is Stimulated by a Novel Agonist of the ClC-2 Chloride Channel, Lubiprostone-Previous studies utiliz...

Molecular Investigation of the Intestinal Barrier in Health and Disease

Ebangwese, Santita

May 2019

The intestinal epithelial barrier contributes to the absorption of nutrients and in maintaining home...

Role of goblet cell protein CLCA1 in murine DSS colitis

Erickson, Nancy A.
Mundhenk, Lars
Giovannini, Samoa
Glauben, Rainer
Heimesaat, Markus M.
Gruber, Achim D.

January 2016

Background The secreted goblet cell protein CLCA1 (chloride channel regulator, calcium-activated-1) ...

Desmoglein2 Regulates Claudin2 Expression by Sequestering PI-3-Kinase in Intestinal Epithelial Cells

Burkard, Natalie
Meir, Michael
Kannapin, Felix
Otto, Christoph
Petzke, Maximilian
Germer, Christoph-Thomas
Waschke, Jens
Schlegel, Nicolas

January 2021

Inflammation-induced reduction of intestinal desmosomal cadherin Desmoglein 2 (Dsg2) is linked to ch...

Desmoglein2 Regulates Claudin2 Expression by Sequestering PI-3-Kinase in Intestinal Epithelial Cells

Natalie Burkard
Michael Meir
Felix Kannapin
Christoph Otto
Maximilian Petzke
Christoph-Thomas Germer
Jens Waschke
Nicolas Schlegel

September 2021

Inflammation-induced reduction of intestinal desmosomal cadherin Desmoglein 2 (Dsg2) is linked to ch...

Desmoglein2 Regulates Claudin2 Expression by Sequestering PI-3-Kinase in Intestinal Epithelial Cells

Burkard, Natalie
Meir, Michael
Kannapin, Felix
Otto, Christoph
Petzke, Maximilian
Germer, Christoph-Thomas
Waschke, Jens
Schlegel, Nicolas

January 2021

Inflammation-induced reduction of intestinal desmosomal cadherin Desmoglein 2 (Dsg2) is linked to ch...

Desmoglein2 Regulates Claudin2 Expression by Sequestering PI-3-Kinase in Intestinal Epithelial Cells

Burkard, Natalie
Meir, Michael
Kannapin, Felix
Otto, Christoph
Petzke, Maximilian
Germer, Christoph-Thomas
Waschke, Jens
Schlegel, Nicolas

January 2021

Inflammation-induced reduction of intestinal desmosomal cadherin Desmoglein 2 (Dsg2) is linked to ch...

Microbial products induce claudin-2 to compromise gut epithelial barrier function.

Xiaoyu Liu
Gui Yang
Xiao-Rui Geng
Yanjuan Cao
Na Li
Li Ma
Si Chen
Ping-Chang Yang
Zhigang Liu

The epithelial barrier dysfunction is an important pathogenic feature in a number of diseases. The u...

Chloride Channel ClC-2 is a Key Factor in the Development of DSS-induced Murine Colitis:

Abstract

Extracted data

Chloride Channel ClC-2 is a Key Factor in the Development of DSS-induced Murine Colitis:

Abstract

Extracted data

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