Association testing of TCF7L2 polymorphisms with type 2 diabetes in multi-ethnic youth
- Dabelea, D.
- Dolan, L. M.
- D’Agostino, R.
- Hernandez, A. M.
- McAteer, J. B.
- Hamman, R. F.
- Mayer-Davis, E. J.
- Marcovina, S.
- Lawrence, J. M.
- Pihoker, C.
- Florez, J. C.
Publication date
January 2011
DOIAbstract
Common variants in the transcription factor 7-like 2 (TCF7L2) gene have been associated with type 2 diabetes in adults. However, it is not known whether TCF7L2 variation increases the risk of early onset type 2 diabetes. Using a case–control design, we examined whether the reported variants [rs12255372 (T/G) and rs7903146 (T/C)] are associated with type 2 diabetes in SEARCH for Diabetes in Youth study participants
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