Primary immunodeficiencies (PID) comprise a diverse group of clinical disorders with varied genetic defects. Paradoxically, a substantial proportion of PID patients develop autoimmune phenomena in addition to having increased susceptibility to infections from their impaired immunity. Although much of our understanding comes from data gathered through experimental models, there are several well-characterized PID that have improved our knowledge of the pathways that drive autoimmunity. The goals of this review will be to discuss these immunodeficiencies and to review the literature with respect to the proposed mechanisms for autoimmunity within each put forth to date
2 Background: Primary immunodeficiency diseases (PIDs) comprise a genetically heterogeneous group of...
Primary immune regulatory disorders (PIRDs) are inborn errors of immunity caused by a loss in the re...
Background Several primary immune deficiency disorders are associated with autoimmunity and malignan...
Primary immunodeficiencies (PID) comprise a diverse group of clinical disorders with varied genetic ...
The primary immunodeficiency diseases (PIDs) include many genetic disorders that affect different co...
Increased risk of developing autoimmune manifestations has been identified in different primary immu...
Background Primary Immunodeficiencies (PIDs) represent unique opportunities to understand the operat...
To access publisher full text version of this article. Please click on the hyperlink in Additional L...
Primary immunodeficiencies (PIDs) constitute a large group of rare disorders that affect the functio...
During the last years, studies investigating the intriguing association between immunodeficiency and...
© 2019 Charlotte Ann SladePrimary Immunodeficiencies (PIDs) are a heterogeneous collection of severa...
The immune system is a complex integrated network of chemical and cellular mediators that developed ...
A broad spectrum of autoimmunity is now well described in patients with primary immunodeficiencies (...
Autoimmune disorders (AID) have been increasingly observed in association with primary immunodeficie...
Primary immunodeficiency diseases (PID) provide invaluable insight into immune system, notably in vi...
2 Background: Primary immunodeficiency diseases (PIDs) comprise a genetically heterogeneous group of...
Primary immune regulatory disorders (PIRDs) are inborn errors of immunity caused by a loss in the re...
Background Several primary immune deficiency disorders are associated with autoimmunity and malignan...
Primary immunodeficiencies (PID) comprise a diverse group of clinical disorders with varied genetic ...
The primary immunodeficiency diseases (PIDs) include many genetic disorders that affect different co...
Increased risk of developing autoimmune manifestations has been identified in different primary immu...
Background Primary Immunodeficiencies (PIDs) represent unique opportunities to understand the operat...
To access publisher full text version of this article. Please click on the hyperlink in Additional L...
Primary immunodeficiencies (PIDs) constitute a large group of rare disorders that affect the functio...
During the last years, studies investigating the intriguing association between immunodeficiency and...
© 2019 Charlotte Ann SladePrimary Immunodeficiencies (PIDs) are a heterogeneous collection of severa...
The immune system is a complex integrated network of chemical and cellular mediators that developed ...
A broad spectrum of autoimmunity is now well described in patients with primary immunodeficiencies (...
Autoimmune disorders (AID) have been increasingly observed in association with primary immunodeficie...
Primary immunodeficiency diseases (PID) provide invaluable insight into immune system, notably in vi...
2 Background: Primary immunodeficiency diseases (PIDs) comprise a genetically heterogeneous group of...
Primary immune regulatory disorders (PIRDs) are inborn errors of immunity caused by a loss in the re...
Background Several primary immune deficiency disorders are associated with autoimmunity and malignan...