Pooled Individual Data Analysis of 5 Randomized Trials of Infant Nevirapine Prophylaxis to Prevent Breast-Milk HIV-1 Transmission
- Hudgens, Michael G.
- Taha, Taha E.
- Omer, Saad B.
- Jamieson, Denise J.
- Lee, Hana
- Mofenson, Lynne M.
- Chasela, Charles
- Kourtis, Athena P.
- Kumwenda, Newton
- Ruff, Andrea
- Bedri, Abubaker
- Jackson, J. Brooks
- Musoke, Philippa
- Bollinger, Robert C.
- Gupte, Nikhil
- Thigpen, Michael C.
- Taylor, Allan
- Van Der Horst, Charles
Publication date
January 2013
DOIAbstract
Background. In resource-limited settings, mothers infected with human immunodeficiency virus type 1 (HIV-1) face a difficult choice: breastfeed their infants but risk transmitting HIV-1 or not breastfeed their infants and risk the infants dying of other infectious diseases or malnutrition. Recent results from observational studies and randomized clinical trials indicate daily administration of nevirapine to the infant can prevent breast-milk HIV-1 transmission
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