The ubiquitin-proteasome pathway has been validated as a target in non-Hodgkin lymphoma through demonstration of the activity of the proteasome inhibitor bortezomib
Intracellular proteolytic pathways have been validated as rational targets in multiple myeloma with ...
Therapeutics that disrupt the p53-MDM2 interaction show promise for cancer treatment but surprisingl...
The tumor suppressor p53 is a canonical regulator of different biological functions, like apoptosis,...
The ubiquitin-proteasome pathway has been validated as a target in non-Hodgkin lymphoma through demo...
SummaryThe p53 tumor suppressor protein is regulated by its interaction with HDM2, which serves as a...
The tumor suppressor p53 plays a significant role in a variety of cellular functions including DNA r...
Lymphomas frequently retain wild-type (wt) p53 function but overexpress HDM2, compromising p53 activ...
Intracellular proteolytic pathways have been validated as rational targets in multiple myeloma with ...
© 2014 Dr. Elizabeth J. ValentePublication included in thesis:Valente, L. J., Gray, D. H. D., Michal...
SummaryCancer cells neutralize p53 by deletion, mutation, proteasomal degradation, or sequestration ...
Tumor suppressor p53 is typically maintained at low levels in normal cells. In response to cellular ...
Abstract Background Lymphomas frequently retain wild-type (wt) p53 function but overexpress HDM2, th...
WOS: 000347582200022PubMed ID: 25305590The 26S proteasome is a proteolytic enzyme found in both cyto...
p53 is a prominent tumor suppressor which plays a crucial role in controlling cancer development by ...
SummaryBortezomib therapy has proven successful for the treatment of relapsed/refractory, relapsed, ...
Intracellular proteolytic pathways have been validated as rational targets in multiple myeloma with ...
Therapeutics that disrupt the p53-MDM2 interaction show promise for cancer treatment but surprisingl...
The tumor suppressor p53 is a canonical regulator of different biological functions, like apoptosis,...
The ubiquitin-proteasome pathway has been validated as a target in non-Hodgkin lymphoma through demo...
SummaryThe p53 tumor suppressor protein is regulated by its interaction with HDM2, which serves as a...
The tumor suppressor p53 plays a significant role in a variety of cellular functions including DNA r...
Lymphomas frequently retain wild-type (wt) p53 function but overexpress HDM2, compromising p53 activ...
Intracellular proteolytic pathways have been validated as rational targets in multiple myeloma with ...
© 2014 Dr. Elizabeth J. ValentePublication included in thesis:Valente, L. J., Gray, D. H. D., Michal...
SummaryCancer cells neutralize p53 by deletion, mutation, proteasomal degradation, or sequestration ...
Tumor suppressor p53 is typically maintained at low levels in normal cells. In response to cellular ...
Abstract Background Lymphomas frequently retain wild-type (wt) p53 function but overexpress HDM2, th...
WOS: 000347582200022PubMed ID: 25305590The 26S proteasome is a proteolytic enzyme found in both cyto...
p53 is a prominent tumor suppressor which plays a crucial role in controlling cancer development by ...
SummaryBortezomib therapy has proven successful for the treatment of relapsed/refractory, relapsed, ...
Intracellular proteolytic pathways have been validated as rational targets in multiple myeloma with ...
Therapeutics that disrupt the p53-MDM2 interaction show promise for cancer treatment but surprisingl...
The tumor suppressor p53 is a canonical regulator of different biological functions, like apoptosis,...
DOI
Add to ORKG