Membrane fusion, essential to eukaryotic life, is broadly envisioned as a three-step process proceeding from contacting bilayers through two semistable, nonlamellar lipidic intermediate states to a fusion pore. Here, we introduced a new, to our knowledge, experimental approach to gain insight into the nature of the transition states between initial, intermediate, and final states. Recorded time courses of lipid-mixing, content-mixing, and content-leakage associated with fusion of 23 nm vesicles in the presence of poly(ethylene glycol) at multiple temperatures were fitted globally to a three-step sequential model to yield rate constants and thereby activation thermodynamics for each step of the process, as well as probabilities of occurrence...
Membrane fusion is a key step in intracellular trafficking and viral infection. The underlying molec...
Membrane fusion is a key step in intracellular trafficking and viral infection. The underlying molec...
Membrane fusion is a key step in intracellular trafficking and viral infection. The underlying molec...
Membrane fusion, essential to eukaryotic life, is broadly envisioned as a three-step process proceed...
Membrane fusion, essential to eukaryotic life, is broadly envisioned as a three-step process proceed...
AbstractMembrane fusion, essential to eukaryotic life, is broadly envisioned as a three-step process...
We propose a model that accounts for the time courses of PEG-induced fusion of membrane vesicles of ...
We propose a model that accounts for the time courses of PEG-induced fusion of membrane vesicles of ...
AbstractWe propose a model that accounts for the time courses of PEG-induced fusion of membrane vesi...
AbstractWe propose a model that accounts for the time courses of PEG-induced fusion of membrane vesi...
ABSTRACT We propose a model that accounts for the time courses of PEG-induced fusion of membrane ves...
Here, we examine the different mechanisms of poly(ethylene glycol)-mediated fusion of small unilamel...
AbstractHere, we examine the different mechanisms of poly(ethylene glycol)-mediated fusion of small ...
Here, we examine the different mechanisms of poly(ethylene glycol)-mediated fusion of small unilamel...
Membrane fusion is a key step in intracellular trafficking and viral infection. The underlying molec...
Membrane fusion is a key step in intracellular trafficking and viral infection. The underlying molec...
Membrane fusion is a key step in intracellular trafficking and viral infection. The underlying molec...
Membrane fusion is a key step in intracellular trafficking and viral infection. The underlying molec...
Membrane fusion, essential to eukaryotic life, is broadly envisioned as a three-step process proceed...
Membrane fusion, essential to eukaryotic life, is broadly envisioned as a three-step process proceed...
AbstractMembrane fusion, essential to eukaryotic life, is broadly envisioned as a three-step process...
We propose a model that accounts for the time courses of PEG-induced fusion of membrane vesicles of ...
We propose a model that accounts for the time courses of PEG-induced fusion of membrane vesicles of ...
AbstractWe propose a model that accounts for the time courses of PEG-induced fusion of membrane vesi...
AbstractWe propose a model that accounts for the time courses of PEG-induced fusion of membrane vesi...
ABSTRACT We propose a model that accounts for the time courses of PEG-induced fusion of membrane ves...
Here, we examine the different mechanisms of poly(ethylene glycol)-mediated fusion of small unilamel...
AbstractHere, we examine the different mechanisms of poly(ethylene glycol)-mediated fusion of small ...
Here, we examine the different mechanisms of poly(ethylene glycol)-mediated fusion of small unilamel...
Membrane fusion is a key step in intracellular trafficking and viral infection. The underlying molec...
Membrane fusion is a key step in intracellular trafficking and viral infection. The underlying molec...
Membrane fusion is a key step in intracellular trafficking and viral infection. The underlying molec...
Membrane fusion is a key step in intracellular trafficking and viral infection. The underlying molec...