Polymorphisms in the ICAM1 gene predict circulating soluble intercellular adhesion molecule-1(sICAM-1)
- Bielinski, Suzette J.
- Reiner, Alex P.
- Nickerson, Deborah
- Carlson, Chris
- Bailey, Kent R.
- Thyagarajan, Bharat
- Lange, Leslie A.
- Boerwinkle, Eric A.
- Jacobs, David R.
- Gross, Myron D.
Publication date
January 2011
DOIAbstract
Polymorphisms within the ICAM1 structural gene have been shown to influence circulating levels of soluble intercellular adhesion molecule -1 (sICAM-1) but their relation to atherosclerosis has not been clearly established. We sought to determine whether ICAM1 SNPs are associated with circulating sICAM-1 concentration, coronary artery calcium (CAC), and common and internal carotid intima medial thickness (IMT)
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