Bmper Inhibits Endothelial Expression of Inflammatory Adhesion Molecules and Protects Against Atherosclerosis
- Pi, X.
- Lockyer, P.
- Dyer, L. A.
- Schisler, J. C.
- Russell, B.
- Carey, S.
- Sweet, D. T.
- Chen, Z.
- Tzima, E.
- Willis, M. S.
- Homeister, J. W.
- Moser, M.
- Patterson, C.
Publication date
January 2012
DOIAbstract
Bone morphogenetic proteins (Bmps) are important mediators of inflammation and atherosclerosis, though their mechanism of action is not fully understood. To better understand the contribution of the Bmp signaling pathway plays in vascular inflammation, we investigated the role of Bmper (Bmp-endothelial cell precursor-derived regulator), an extracellular Bmp modulator, in an induced in vivo model of inflammation and atherosclerosis
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