Increased Genetic Vulnerability to Smoking at CHRNA5 in Early-Onset Smokers

Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior.

Thorgeirsson, T.E.
Gudbjartsson, D.F.
Surakka, I.
Vink, J.M.
Amin, N.
Geller, F.
Sulem, P.
Rafnar, T.
Esko, T.
Walter, S.
Gieger, C.
Rawal, R.
Mangino, M.
Prokopenko, I.
Magi, R.
Keskitalo, K.
Gudjonsdottir, I.H.
Gretarsdottir, S.
Stefansson, H.
Thompson, J.R.
Aulchenko, Y.S.
Nelis, M.
Aben, K.K.H.
Heijer, M. den
Dirksen, A.
Ashraf, H.
Soranzo, N.
Valdes, A.M.
Steves, C.
Uitterlinden, A.G.
Hofman, A.
Tonjes, A.
Kovacs, P.
Hottenga, J.J.
Willemsen, G.
Vogelzangs, N.
Doring, A.
Dahmen, N.
Nitz, B.
Pergadia, M.L.
Saez, B.
Diego, V. De
Lezcano, V.
Garcia-Prats, M.D.
Ripatti, S.
Perola, M.
Kettunen, J.
Hartikainen, A.L.
Pouta, A.
Laitinen, J.
Isohanni, M.
Huei-Yi, S.
Allen, M.
Krestyaninova, M.
Hall, A.S.
Jones, G.T.
Rij, A.M. van
Mueller, T.
Dieplinger, B.
Haltmayer, M.
Jonsson, S.
Matthiasson, S.E.
Oskarsson, H.
Tyrfingsson, T.
Kiemeney, L.A.L.M.
Mayordomo, J.I.
Lindholt, J.S.
Pedersen, J.H.
Franklin, W.A.
Wolf, H.
Montgomery, G.W.
Heath, A.C.
Martin, N.G.
Madden, P.A.F.
Giegling, I.
Rujescu, D.
Jarvelin, M.R.
Salomaa, V.
Stumvoll, M.
Spector, T.D.
Wichmann, H.E.
Metspalu, A.
Samani, N.J.
Penninx, B.W.J.H.
Oostra, B.A.
Boomsma, D.I.
Tiemeier, H.
Duijn, C.M. van
Kaprio, J.
Gulcher, J.R.
McCarthy, M.I.
Peltonen, L.
Thorsteinsdottir, U.
Stefansson, K.

January 2010

Contains fulltext : 89305.pdf (publisher's version ) (Closed access)Smoking is a c...

Genetic Risk Can Be Decreased: Quitting Smoking Decreases and Delays Lung Cancer for Smokers With High and Low CHRNA5 Risk Genotypes - A Meta-analysis.

Chen, L.S.
Baker, T.
Hung, R.J.
Horton, A.
Culverhouse, R.
Hartz, S.
Saccone, N.
Cheng, I.
Deng, B.
Han, Y.
Hansen, H.M.
Horsman, J.
Kim, C.
Rosenberger, A.
Aben, K.K.
Andrew, A.S.
Chang, S.C.
Saum, K.U.
Dienemann, H.
Hatsukami, D.K.
Johnson, E.O.
Pande, M.
Wrensch, M.R.
McLaughlin, J.
Skaug, V.
van der Heijden, E.H.
Wampfler, J.
Wenzlaff, A.
Woll, P.
Zienolddiny, S.
Bickeböller, H.
Brenner, H.
Duell, E.J.
Haugen, A.
Brüske, I.
Kiemeney, L.A.
Lazarus, P.
Le Marchand, L.
Liu, G.
Mayordomo, J.
Risch, A.
Schwartz, A.G.
Teare, M.D.
Wu, X.
Wiencke, J.K.
Yang, P.
Zhang, Z.F.
Spitz, M.R.
Amos, C.I.
Bierut, L.J.

August 2016

BACKGROUND: Recent meta-analyses show that individuals with high risk variants in CHRNA5 on chromoso...

EBioMedicine / Genetic risk can be decreased : quitting smoking decreases and delays lung cancer for smokers with high and low CHRNA5 risk genotypes - a meta-analysis.

Chen, Li-Shiun
Baker, Timothy
Hung, Rayjean J.
Horton, Amy
Culverhouse, Robert
Hartz, Sarah
Saccone, Nancy
Cheng, Iona
Deng, Bo
Han, Younghun
Hansen, Helen M.
Horsman, Janet
Kim, Claire
Rosenberger, Albert
Aben, Katja K.
Andrew, Angeline S.
Chang, Shen-Chi
Saum, Kai-Uwe
Dienemann, Hendrick
Hatsukami, Dorothy K.
Johnson, Eric O.
Pande, Mala
Wrensch, Margaret R.
McLaughlin, John
Risch, Angela

January 2016

BACKGROUND: Recent meta-analyses show that individuals with high risk variants in CHRNA5 on chromoso...

Increased Genetic Vulnerability to Smoking at CHRNA5 in Early-Onset Smokers

Hartz, Sarah M.
Short, Susan E.
Saccone, Nancy L.
Culverhouse, Robert
Chen, LiShiun
Schwantes-An, Tae-Hwi
Coon, Hilary
Han, Younghun
Stephens, Sarah H.
Sun, Juzhong
Chen, Xiangning
Ducci, Francesca
Dueker, Nicole
Franceschini, Nora
Frank, Josef
Geller, Frank
Gubjartsson, Daniel
Hansel, Nadia N.
Jiang, Chenhui
Keskitalo-Vuokko, Kaisu
Liu, Zhen
Lyytikäinen, Leo-Pekka
Michel, Martha
Rawal, Rajesh
Rosenberger, Albert
Scheet, Paul
Shaffer, John R.
Teumer, Alexander
Thompson, John R.
Vink, Jacqueline M.
Vogelzangs, Nicole
Wenzlaff, Angela S.

January 2012

Recent studies have shown an association between cigarettes per day (CPD) and a nonsynonymous single...

Increased genetic vulnerability to smoking at CHRNA5 in early-onset smokers

Hartz , S.
Short, S.
Saccone, N.
Culverhouse, R.
Chen, L.
Schwantes-An, T.
Coon, H.
Han, Y.
Stephens, S.
Sun , J.
Chen, X.
Ducci , F.
Dueker, N.
Franceschini , N.
Frank, J.
Geller, F.
Gubjartsson, D.
Hansel, N.
Jiang, C.
Keskitalo-Vuokko, K.
Liu, Z.
Lyytikainen, L.
Michel, M.
Rawal, R.
Rosenberger, A.
Scheet, P.
Shaffer, J.
Teumer, A.
Thompson, J.
Vink, J.
Vogelzangs, N.
Wenzlaff, A.
Wheeler, W.
Xiao, X.
Yang, B.
Aggen, S.
Balmforth, A.
Baumeister, S.
Beaty, T.
Bennett, S.
Bergen, A.
Boyd, H.
Broms, U.
Campbell, H.
Chatterjee, N.
Chen , J.
Cheng, Y.
Cichon, S.
Couper, D.
Cucca, F.
Dick, D.
Foroud, T.
Furberg , H.
Giegling, I.
Gu, F.
Hall, A.
Hallfors, J.
Han, S.
Hartmann, A.
Hayward, C.
Heikkila, K.
Hewitt, J.
Hottenga, J.
Jensen, M.
Jousilahti , P.
Kaakinen, M.
Kittner , S.
Konte, B.
Korhonen, T.
Landi, M.
Laatikainen , T.
Leppert, M.
Levy , S.
Mathias, R.
McNeil, D.
Medland, S.
Montgomery, G.
Muley, T.
Murray, T.
Nauck, M.
North, K.
Pergadia, M.
Polasek , O.
Ramos, E.
Ripatti, S.
Risch, A.
Ruczinski, I.
Rudan , I.
Salomaa , V.
Schlessinger, D.
Styrkarsdottir, U.
Terracciano, A.
Uda, M.
Willemsen, G.
Wu , X.
Abecasis, G.
Barnes, K.
Bickeboller, H.
Boerwinkle, E.
Boomsma, D.
Caporaso, N.
Duan, J.
Edenberg, H.
Francks, C.
Gejman, P.
Gelernter, J.
Grabe, H.
Hops, H.
Jarvelin , M.
Viikari , J.
Kahonen , M.
Kendler, K.
Lehtimaki , T.
Levinson, D.
Marazita, M.
Marchini , J.
Melbye , M.
Mitchell , B.
Murray, J.
Nothen, M.
Penninx, B.
Raitakari , O.
Rietschel, M.
Rujescu, D.
Samani, N.
Sanders, A.
Schwartz, A.
Shete, S.
Shi, J.
Spitz, M.
Stefansson , K.
Swan, G.
Thorgeirsson, T.
Volzke, H.
Wei, Q.
Wichmann , H.
Amos, C.
Breslau, N.
Cannon, D.
Ehringer, M.
Grucza, R.
Hatsukami, D.
Heath, A.
Johnson, E.
Kaprio, J.
Madden, P.
Martin, N.
Stevens, V.
Stitzel, J.
Weiss, R.
Kraft, P.
Bierut, L.

January 2012

CONTEXT Recent studies have shown an association between cigarettes per day (CPD) and a nonsynonymou...

Increased genetic vulnerability to smoking at <em>CHRNA5</em> in early-onset smokers.

Hartz, S.M.
Short, S.E.
Saccone, N.L.
Culverhouse, R.
Chen, L.
Schwantes-An, T.H.
Coon, H.
Han, Y.
Stephens, S.H.
Sun, J.
Chen, X.
Ducci, F.
Dueker, N.
Franceschini, N.
Frank, J.
Geller, F.
Gubjartsson, D.
Hansel, N.N.
Jiang, C.
Keskitalo-Vuokko, K.
Liu, Z.
Lyytikäinen, L.-P.
Michel, M.
Rawal, R.
Rosenberger, A.
Scheet, P.
Shaffer, J.R.
Teumer, A.
Thompson, J.R.
Vink, J.M.
Vogelzangs, N.
Wenzlaff, A.S.
Wheeler, W.
Xiao, X.
Yang, B.Z.
Aggen, S.H.
Balmforth, A.J.
Baumeister, S.E.
Beaty, T.
Bennett, S.
Bergen, A.W.
Boyd, H.A.
Broms, U.
Campbell, H.
Chatterjee, N.
Chen, J.
Cheng, Y.C.
Cichon, S.
Couper, D.
Cucca, F.
Dick, D.M.
Foroud, T.
Furberg, H.
Giegling, I.
Gu, F.
Hall, A.S.
Hällfors, J.
Han, S.
Hartmann, A.M.
Hayward, C.
Heikkilä, K.
Hewitt, J.K.
Hottenga, J.J.
Jensen, M.K.
Jousilahti, P.
Kaakinen, M.
Kittner, S.J.
Konte, B.
Korhonen, T.
Landi, M.T.
Laatikainen, T.
Leppert, M.
Levy, S.M.
Mathias, R.A.
McNeil, D.W.
Medland, S.E.
Montgomery, G.W.
Muley, T.
Murray, T.
Nauck, M.
North, K.
Pergadia, M.
Polasek, O.
Ramos, E.M.
Ripatti, S.
Risch, A.
Ruczinski, I.
Rudan, I.
Salomaa, V.
Schlessinger, D.
Styrkarsdottir, U.
Terracciano, A.
Uda, M.
Willemsen, G.
Wu, X.
Abecasis, G.
Barnes, K.
Bickeböller, H.
Boerwinkle, E.
Boomsma, D.I.
Caporaso, N.
Duan, J.
Edenberg, H.J.
Francks, C.
Gejman, P.V.
Gelernter, J.
Grabe, H.J.
Hops, H.
Jarvelin, M.R.
Viikari, J.
Kähönen, M.
Kendler, K.S.
Lehtimäki, T.
Levinson, D.F.
Marazita, M.L.
Marchini, J.
Melbye, M.
Mitchell, B.D.
Murray, J.C.
Nöthen, M.M.
Penninx, B.W.
Raitakari, O.
Rietschel, M.
Rujescu, D.
Samani, N.J.
Sanders, A.R.
Schwartz, A.G.
Shete, S.
Shi, J.
Spitz, M.
Stefansson, K.
Swan, G.E.
Thorgeirsson, T.
Völzke, H.
Wei, Q.
Wichmann, H.-E.
Amos, C.I.
Breslau, N.
Cannon, D.S.
Ehringer, M.
Grucza, R.
Hatsukami, D.
Heath, A.
Johnson, E.O.
Kaprio, J.
Madden, P.
Martin, N.G.
Stevens, V.L.
Stitzel, J.A.
Weiss, R.B.
Kraft, P.
Bierut, L.J.

January 2012

CONTEXT Recent studies have shown an association between cigarettes per day (CPD) and a nonsynonymou...

Increased genetic vulnerability to smoking at CHRNA5 in early-onset smokers.

Hartz, S
Short, SE
Saccone, N
Culverhouse, R
Chen, L
Schwantes-An, T
Coon, H
Han, Y
Stephens, S
Sun, J
Chen, X
Ducci, F
Dueker, N
Franceschini, N
Frank, J
Geller, F
Gubjartsson, D
Hansel, N
Jiang, C
Keskitalo-Vuokko, K
Liu, Z
Lyytikäinen, L
Michel, M
Rawal, R
Rosenberger, A

January 2012

CONTEXT: Recent studies have shown an association between cigarettes per day (CPD) and a nonsynonymo...

Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior

Thorgeirsson, Thorgeir E
Gudbjartsson, Daniel F
Surakka, Ida
Vink, Jacqueline M
Amin, Najaf
Geller, Frank
Sulem, Patrick
Rafnar, Thorunn
Esko, Tõnu
Walter, Stefan
Gieger, Christian
Rawal, Rajesh
Mangino, Massimo
Prokopenko, Inga
Mägi, Reedik
Keskitalo, Kaisu
Gudjonsdottir, Iris H
Gretarsdottir, Solveig
Stefansson, Hreinn
Thompson, John R
Aulchenko, Yurii S
Nelis, Mari
Aben, Katja K
den Heijer, Martin
Dirksen, Asger
Ashraf, Haseem
Soranzo, Nicole
Valdes, Ana M
Steves, Claire
Uitterlinden, André G
Hofman, Albert
Tönjes, Anke
Kovacs, Peter
Hottenga, Jouke Jan
Willemsen, Gonneke
Vogelzangs, Nicole
Döring, Angela
Dahmen, Norbert
Nitz, Barbara
Pergadia, Michele L
Saez, Berta
De Diego, Veronica
Lezcano, Victoria
Garcia-Prats, Maria D
Ripatti, Samuli
Perola, Markus
Kettunen, Johannes
Hartikainen, Anna-Liisa
Pouta, Anneli
Laitinen, Jaana
Isohanni, Matti
Huei-Yi, Shen
Allen, Maxine
Krestyaninova, Maria
Hall, Alistair S
Jones, Gregory T
van Rij, Andre M
Mueller, Thomas
Dieplinger, Benjamin
Haltmayer, Meinhard
Jonsson, Steinn
Matthiasson, Stefan E
Oskarsson, Hogni
Tyrfingsson, Thorarinn
Kiemeney, Lambertus A
Mayordomo, Jose I
Lindholt, Jes S
Pedersen, Jesper Holst
Franklin, Wilbur A
Wolf, Holly
Montgomery, Grant W
Heath, Andrew C
Martin, Nicholas G
Madden, Pamela A F
Giegling, Ina
Rujescu, Dan
Järvelin, Marjo-Riitta
Salomaa, Veikko
Stumvoll, Michael
Spector, Tim D
Wichmann, H-Erich
Metspalu, Andres
Samani, Nilesh J
Penninx, Brenda W
Oostra, Ben A
Boomsma, Dorret I
Tiemeier, Henning
van Duijn, Cornelia M
Kaprio, Jaakko
Gulcher, Jeffrey R
McCarthy, Mark I
Peltonen, Leena
Thorsteinsdottir, Unnur
Stefansson, Kari

June 2010

To access publisher full text version of this article. Please click on the hyperlink in Additional L...

Exploring associations between the nicotinic acetylcholine receptor gene cluster CHRNA5-A3-B4 and smoking-related behaviours

Ware, Jennifer J.

Tobacco use is the leading preventable cause of death worldwide. In order to address this epidemic, ...

Genetic Risk Can Be Decreased: Quitting Smoking Decreases and Delays Lung Cancer for Smokers With High and Low CHRNA5 Risk Genotypes — A Meta-Analysis

Chen, Li-Shiun
Baker, Timothy
Hung, Rayjean J.
Horton, Amy
Culverhouse, Robert
Hartz, Sarah
Saccone, Nancy
Cheng, Iona
Deng, Bo
Han, Younghun
Hansen, Helen M.
Horsman, Janet
Kim, Claire
Rosenberger, Albert
Aben, Katja K.
Andrew, Angeline S.
Chang, Shen-Chih
Saum, Kai-Uwe
Dienemann, Hendrik
Hatsukami, Dorothy K.
Johnson, Eric O.
Pande, Mala
Wrensch, Margaret R.
McLaughlin, John
Skaug, Vidar
van der Heijden, Erik H.
Wampfler, Jason
Wenzlaff, Angela
Woll, Penella
Zienolddiny, Shanbeh
Bickeböller, Heike
Brenner, Hermann
Duell, Eric J.
Haugen, Aage
Brüske, Irene
Kiemeney, Lambertus A.
Lazarus, Philip
Le Marchand, Loic
Liu, Geoffrey
Mayordomo, Jose
Risch, Angela
Schwartz, Ann G.
Teare, M. Dawn
Wu, Xifeng
Wiencke, John K.
Yang, Ping
Zhang, Zuo-Feng
Spitz, Margaret R.
Amos, Christopher I.
Bierut, Laura J.

September 2016

AbstractBackgroundRecent meta-analyses show that individuals with high risk variants in CHRNA5 on ch...

Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci

Erzurumluoglu, A. Mesut
Liu, Mengzhen
Jackson, Victoria E.
Barnes, Daniel R.
Datta, Gargi
Melbourne, Carl A.
Young, Robin
Batini, Chiara
Surendran, Praveen
Jiang, Tao
Adnan, Sheikh Daud
Afaq, Saima
Agrawal, Arpana
Altmaier, Elisabeth
Antoniou, Antonis C.
Asselbergs, Folkert W.
Baumbach, Clemens
Bierut, Laura
Bertelsen, Sarah
Boehnke, Michael
Bots, Michiel L.
Brazel, David M.
Chambers, John C.
Chang-Claude, Jenny
Chen, Chu
Corley, Janie
Chou, Yi Ling
David, Sean P.
de Boer, Rudolf A.
de Leeuw, Christiaan A.
Dennis, Joe G.
Dominiczak, Anna F.
Dunning, Alison M.
Easton, Douglas F.
Eaton, Charles
Elliott, Paul
Evangelou, Evangelos
Faul, Jessica D.
Foroud, Tatiana
Goate, Alison
Gong, Jian
Grabe, Hans J.
Haessler, Jeff
Haiman, Christopher
Hallmans, Göran
Hammerschlag, Anke R.
Harris, Sarah E.
Smith, Jennifer A.
Zhou, Kaixin
Palmer, Colin N.A.
Liu, Dajiang J.
Howson, Joanna M. M.

October 2020

Smoking is a major heritable and modifiable risk factor for many diseases, including cancer, common ...

Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior.

Thorgeirsson, T.E.
Gudbjartsson, D.F.
Surakka, I.
Vink, J.M.
Amin, N.
Geller, F.
Sulem, P.
Rafnar, T.
Esko, T.
Walter, S.
Gieger, C.
Rawal, R.
Mangino, M.
Prokopenko, I.
Magi, R.
Keskitalo, K.
Gudjonsdottir, I.H.
Gretarsdottir, S.
Stefansson, H.
Thompson, J.R.
Aulchenko, Y.S.
Nelis, M.
Aben, K.K.H.
Heijer, M. den
Dirksen, A.
Ashraf, H.
Soranzo, N.
Valdes, A.M.
Steves, C.
Uitterlinden, A.G.
Hofman, A.
Tonjes, A.
Kovacs, P.
Hottenga, J.J.
Willemsen, G.
Vogelzangs, N.
Doring, A.
Dahmen, N.
Nitz, B.
Pergadia, M.L.
Saez, B.
Diego, V. De
Lezcano, V.
Garcia-Prats, M.D.
Ripatti, S.
Perola, M.
Kettunen, J.
Hartikainen, A.L.
Pouta, A.
Laitinen, J.
Isohanni, M.
Huei-Yi, S.
Allen, M.
Krestyaninova, M.
Hall, A.S.
Jones, G.T.
Rij, A.M. van
Mueller, T.
Dieplinger, B.
Haltmayer, M.
Jonsson, S.
Matthiasson, S.E.
Oskarsson, H.
Tyrfingsson, T.
Kiemeney, L.A.L.M.
Mayordomo, J.I.
Lindholt, J.S.
Pedersen, J.H.
Franklin, W.A.
Wolf, H.
Montgomery, G.W.
Heath, A.C.
Martin, N.G.
Madden, P.A.F.
Giegling, I.
Rujescu, D.
Jarvelin, M.R.
Salomaa, V.
Stumvoll, M.
Spector, T.D.
Wichmann, H.E.
Metspalu, A.
Samani, N.J.
Penninx, B.W.J.H.
Oostra, B.A.
Boomsma, D.I.
Tiemeier, H.
Duijn, C.M. van
Kaprio, J.
Gulcher, J.R.
McCarthy, M.I.
Peltonen, L.
Thorsteinsdottir, U.
Stefansson, K.

January 2010

Contains fulltext : 89305.pdf (publisher's version ) (Closed access)Smoking is a c...

Genetic Risk Can Be Decreased: Quitting Smoking Decreases and Delays Lung Cancer for Smokers With High and Low CHRNA5 Risk Genotypes - A Meta-analysis.

Chen, L.S.
Baker, T.
Hung, R.J.
Horton, A.
Culverhouse, R.
Hartz, S.
Saccone, N.
Cheng, I.
Deng, B.
Han, Y.
Hansen, H.M.
Horsman, J.
Kim, C.
Rosenberger, A.
Aben, K.K.
Andrew, A.S.
Chang, S.C.
Saum, K.U.
Dienemann, H.
Hatsukami, D.K.
Johnson, E.O.
Pande, M.
Wrensch, M.R.
McLaughlin, J.
Skaug, V.
van der Heijden, E.H.
Wampfler, J.
Wenzlaff, A.
Woll, P.
Zienolddiny, S.
Bickeböller, H.
Brenner, H.
Duell, E.J.
Haugen, A.
Brüske, I.
Kiemeney, L.A.
Lazarus, P.
Le Marchand, L.
Liu, G.
Mayordomo, J.
Risch, A.
Schwartz, A.G.
Teare, M.D.
Wu, X.
Wiencke, J.K.
Yang, P.
Zhang, Z.F.
Spitz, M.R.
Amos, C.I.
Bierut, L.J.

August 2016

BACKGROUND: Recent meta-analyses show that individuals with high risk variants in CHRNA5 on chromoso...

EBioMedicine / Genetic risk can be decreased : quitting smoking decreases and delays lung cancer for smokers with high and low CHRNA5 risk genotypes - a meta-analysis.

Chen, Li-Shiun
Baker, Timothy
Hung, Rayjean J.
Horton, Amy
Culverhouse, Robert
Hartz, Sarah
Saccone, Nancy
Cheng, Iona
Deng, Bo
Han, Younghun
Hansen, Helen M.
Horsman, Janet
Kim, Claire
Rosenberger, Albert
Aben, Katja K.
Andrew, Angeline S.
Chang, Shen-Chi
Saum, Kai-Uwe
Dienemann, Hendrick
Hatsukami, Dorothy K.
Johnson, Eric O.
Pande, Mala
Wrensch, Margaret R.
McLaughlin, John
Risch, Angela

January 2016

BACKGROUND: Recent meta-analyses show that individuals with high risk variants in CHRNA5 on chromoso...

Increased Genetic Vulnerability to Smoking at CHRNA5 in Early-Onset Smokers

Hartz, Sarah M.
Short, Susan E.
Saccone, Nancy L.
Culverhouse, Robert
Chen, LiShiun
Schwantes-An, Tae-Hwi
Coon, Hilary
Han, Younghun
Stephens, Sarah H.
Sun, Juzhong
Chen, Xiangning
Ducci, Francesca
Dueker, Nicole
Franceschini, Nora
Frank, Josef
Geller, Frank
Gubjartsson, Daniel
Hansel, Nadia N.
Jiang, Chenhui
Keskitalo-Vuokko, Kaisu
Liu, Zhen
Lyytikäinen, Leo-Pekka
Michel, Martha
Rawal, Rajesh
Rosenberger, Albert
Scheet, Paul
Shaffer, John R.
Teumer, Alexander
Thompson, John R.
Vink, Jacqueline M.
Vogelzangs, Nicole
Wenzlaff, Angela S.

January 2012

Recent studies have shown an association between cigarettes per day (CPD) and a nonsynonymous single...

Increased genetic vulnerability to smoking at CHRNA5 in early-onset smokers

Hartz , S.
Short, S.
Saccone, N.
Culverhouse, R.
Chen, L.
Schwantes-An, T.
Coon, H.
Han, Y.
Stephens, S.
Sun , J.
Chen, X.
Ducci , F.
Dueker, N.
Franceschini , N.
Frank, J.
Geller, F.
Gubjartsson, D.
Hansel, N.
Jiang, C.
Keskitalo-Vuokko, K.
Liu, Z.
Lyytikainen, L.
Michel, M.
Rawal, R.
Rosenberger, A.
Scheet, P.
Shaffer, J.
Teumer, A.
Thompson, J.
Vink, J.
Vogelzangs, N.
Wenzlaff, A.
Wheeler, W.
Xiao, X.
Yang, B.
Aggen, S.
Balmforth, A.
Baumeister, S.
Beaty, T.
Bennett, S.
Bergen, A.
Boyd, H.
Broms, U.
Campbell, H.
Chatterjee, N.
Chen , J.
Cheng, Y.
Cichon, S.
Couper, D.
Cucca, F.
Dick, D.
Foroud, T.
Furberg , H.
Giegling, I.
Gu, F.
Hall, A.
Hallfors, J.
Han, S.
Hartmann, A.
Hayward, C.
Heikkila, K.
Hewitt, J.
Hottenga, J.
Jensen, M.
Jousilahti , P.
Kaakinen, M.
Kittner , S.
Konte, B.
Korhonen, T.
Landi, M.
Laatikainen , T.
Leppert, M.
Levy , S.
Mathias, R.
McNeil, D.
Medland, S.
Montgomery, G.
Muley, T.
Murray, T.
Nauck, M.
North, K.
Pergadia, M.
Polasek , O.
Ramos, E.
Ripatti, S.
Risch, A.
Ruczinski, I.
Rudan , I.
Salomaa , V.
Schlessinger, D.
Styrkarsdottir, U.
Terracciano, A.
Uda, M.
Willemsen, G.
Wu , X.
Abecasis, G.
Barnes, K.
Bickeboller, H.
Boerwinkle, E.
Boomsma, D.
Caporaso, N.
Duan, J.
Edenberg, H.
Francks, C.
Gejman, P.
Gelernter, J.
Grabe, H.
Hops, H.
Jarvelin , M.
Viikari , J.
Kahonen , M.
Kendler, K.
Lehtimaki , T.
Levinson, D.
Marazita, M.
Marchini , J.
Melbye , M.
Mitchell , B.
Murray, J.
Nothen, M.
Penninx, B.
Raitakari , O.
Rietschel, M.
Rujescu, D.
Samani, N.
Sanders, A.
Schwartz, A.
Shete, S.
Shi, J.
Spitz, M.
Stefansson , K.
Swan, G.
Thorgeirsson, T.
Volzke, H.
Wei, Q.
Wichmann , H.
Amos, C.
Breslau, N.
Cannon, D.
Ehringer, M.
Grucza, R.
Hatsukami, D.
Heath, A.
Johnson, E.
Kaprio, J.
Madden, P.
Martin, N.
Stevens, V.
Stitzel, J.
Weiss, R.
Kraft, P.
Bierut, L.

January 2012

CONTEXT Recent studies have shown an association between cigarettes per day (CPD) and a nonsynonymou...

Increased genetic vulnerability to smoking at <em>CHRNA5</em> in early-onset smokers.

Hartz, S.M.
Short, S.E.
Saccone, N.L.
Culverhouse, R.
Chen, L.
Schwantes-An, T.H.
Coon, H.
Han, Y.
Stephens, S.H.
Sun, J.
Chen, X.
Ducci, F.
Dueker, N.
Franceschini, N.
Frank, J.
Geller, F.
Gubjartsson, D.
Hansel, N.N.
Jiang, C.
Keskitalo-Vuokko, K.
Liu, Z.
Lyytikäinen, L.-P.
Michel, M.
Rawal, R.
Rosenberger, A.
Scheet, P.
Shaffer, J.R.
Teumer, A.
Thompson, J.R.
Vink, J.M.
Vogelzangs, N.
Wenzlaff, A.S.
Wheeler, W.
Xiao, X.
Yang, B.Z.
Aggen, S.H.
Balmforth, A.J.
Baumeister, S.E.
Beaty, T.
Bennett, S.
Bergen, A.W.
Boyd, H.A.
Broms, U.
Campbell, H.
Chatterjee, N.
Chen, J.
Cheng, Y.C.
Cichon, S.
Couper, D.
Cucca, F.
Dick, D.M.
Foroud, T.
Furberg, H.
Giegling, I.
Gu, F.
Hall, A.S.
Hällfors, J.
Han, S.
Hartmann, A.M.
Hayward, C.
Heikkilä, K.
Hewitt, J.K.
Hottenga, J.J.
Jensen, M.K.
Jousilahti, P.
Kaakinen, M.
Kittner, S.J.
Konte, B.
Korhonen, T.
Landi, M.T.
Laatikainen, T.
Leppert, M.
Levy, S.M.
Mathias, R.A.
McNeil, D.W.
Medland, S.E.
Montgomery, G.W.
Muley, T.
Murray, T.
Nauck, M.
North, K.
Pergadia, M.
Polasek, O.
Ramos, E.M.
Ripatti, S.
Risch, A.
Ruczinski, I.
Rudan, I.
Salomaa, V.
Schlessinger, D.
Styrkarsdottir, U.
Terracciano, A.
Uda, M.
Willemsen, G.
Wu, X.
Abecasis, G.
Barnes, K.
Bickeböller, H.
Boerwinkle, E.
Boomsma, D.I.
Caporaso, N.
Duan, J.
Edenberg, H.J.
Francks, C.
Gejman, P.V.
Gelernter, J.
Grabe, H.J.
Hops, H.
Jarvelin, M.R.
Viikari, J.
Kähönen, M.
Kendler, K.S.
Lehtimäki, T.
Levinson, D.F.
Marazita, M.L.
Marchini, J.
Melbye, M.
Mitchell, B.D.
Murray, J.C.
Nöthen, M.M.
Penninx, B.W.
Raitakari, O.
Rietschel, M.
Rujescu, D.
Samani, N.J.
Sanders, A.R.
Schwartz, A.G.
Shete, S.
Shi, J.
Spitz, M.
Stefansson, K.
Swan, G.E.
Thorgeirsson, T.
Völzke, H.
Wei, Q.
Wichmann, H.-E.
Amos, C.I.
Breslau, N.
Cannon, D.S.
Ehringer, M.
Grucza, R.
Hatsukami, D.
Heath, A.
Johnson, E.O.
Kaprio, J.
Madden, P.
Martin, N.G.
Stevens, V.L.
Stitzel, J.A.
Weiss, R.B.
Kraft, P.
Bierut, L.J.

January 2012

CONTEXT Recent studies have shown an association between cigarettes per day (CPD) and a nonsynonymou...

Increased genetic vulnerability to smoking at CHRNA5 in early-onset smokers.

Hartz, S
Short, SE
Saccone, N
Culverhouse, R
Chen, L
Schwantes-An, T
Coon, H
Han, Y
Stephens, S
Sun, J
Chen, X
Ducci, F
Dueker, N
Franceschini, N
Frank, J
Geller, F
Gubjartsson, D
Hansel, N
Jiang, C
Keskitalo-Vuokko, K
Liu, Z
Lyytikäinen, L
Michel, M
Rawal, R
Rosenberger, A

January 2012

CONTEXT: Recent studies have shown an association between cigarettes per day (CPD) and a nonsynonymo...

Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior

Thorgeirsson, Thorgeir E
Gudbjartsson, Daniel F
Surakka, Ida
Vink, Jacqueline M
Amin, Najaf
Geller, Frank
Sulem, Patrick
Rafnar, Thorunn
Esko, Tõnu
Walter, Stefan
Gieger, Christian
Rawal, Rajesh
Mangino, Massimo
Prokopenko, Inga
Mägi, Reedik
Keskitalo, Kaisu
Gudjonsdottir, Iris H
Gretarsdottir, Solveig
Stefansson, Hreinn
Thompson, John R
Aulchenko, Yurii S
Nelis, Mari
Aben, Katja K
den Heijer, Martin
Dirksen, Asger
Ashraf, Haseem
Soranzo, Nicole
Valdes, Ana M
Steves, Claire
Uitterlinden, André G
Hofman, Albert
Tönjes, Anke
Kovacs, Peter
Hottenga, Jouke Jan
Willemsen, Gonneke
Vogelzangs, Nicole
Döring, Angela
Dahmen, Norbert
Nitz, Barbara
Pergadia, Michele L
Saez, Berta
De Diego, Veronica
Lezcano, Victoria
Garcia-Prats, Maria D
Ripatti, Samuli
Perola, Markus
Kettunen, Johannes
Hartikainen, Anna-Liisa
Pouta, Anneli
Laitinen, Jaana
Isohanni, Matti
Huei-Yi, Shen
Allen, Maxine
Krestyaninova, Maria
Hall, Alistair S
Jones, Gregory T
van Rij, Andre M
Mueller, Thomas
Dieplinger, Benjamin
Haltmayer, Meinhard
Jonsson, Steinn
Matthiasson, Stefan E
Oskarsson, Hogni
Tyrfingsson, Thorarinn
Kiemeney, Lambertus A
Mayordomo, Jose I
Lindholt, Jes S
Pedersen, Jesper Holst
Franklin, Wilbur A
Wolf, Holly
Montgomery, Grant W
Heath, Andrew C
Martin, Nicholas G
Madden, Pamela A F
Giegling, Ina
Rujescu, Dan
Järvelin, Marjo-Riitta
Salomaa, Veikko
Stumvoll, Michael
Spector, Tim D
Wichmann, H-Erich
Metspalu, Andres
Samani, Nilesh J
Penninx, Brenda W
Oostra, Ben A
Boomsma, Dorret I
Tiemeier, Henning
van Duijn, Cornelia M
Kaprio, Jaakko
Gulcher, Jeffrey R
McCarthy, Mark I
Peltonen, Leena
Thorsteinsdottir, Unnur
Stefansson, Kari

June 2010

To access publisher full text version of this article. Please click on the hyperlink in Additional L...

Exploring associations between the nicotinic acetylcholine receptor gene cluster CHRNA5-A3-B4 and smoking-related behaviours

Ware, Jennifer J.

Tobacco use is the leading preventable cause of death worldwide. In order to address this epidemic, ...

Genetic Risk Can Be Decreased: Quitting Smoking Decreases and Delays Lung Cancer for Smokers With High and Low CHRNA5 Risk Genotypes — A Meta-Analysis

Chen, Li-Shiun
Baker, Timothy
Hung, Rayjean J.
Horton, Amy
Culverhouse, Robert
Hartz, Sarah
Saccone, Nancy
Cheng, Iona
Deng, Bo
Han, Younghun
Hansen, Helen M.
Horsman, Janet
Kim, Claire
Rosenberger, Albert
Aben, Katja K.
Andrew, Angeline S.
Chang, Shen-Chih
Saum, Kai-Uwe
Dienemann, Hendrik
Hatsukami, Dorothy K.
Johnson, Eric O.
Pande, Mala
Wrensch, Margaret R.
McLaughlin, John
Skaug, Vidar
van der Heijden, Erik H.
Wampfler, Jason
Wenzlaff, Angela
Woll, Penella
Zienolddiny, Shanbeh
Bickeböller, Heike
Brenner, Hermann
Duell, Eric J.
Haugen, Aage
Brüske, Irene
Kiemeney, Lambertus A.
Lazarus, Philip
Le Marchand, Loic
Liu, Geoffrey
Mayordomo, Jose
Risch, Angela
Schwartz, Ann G.
Teare, M. Dawn
Wu, Xifeng
Wiencke, John K.
Yang, Ping
Zhang, Zuo-Feng
Spitz, Margaret R.
Amos, Christopher I.
Bierut, Laura J.

September 2016

AbstractBackgroundRecent meta-analyses show that individuals with high risk variants in CHRNA5 on ch...

Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci

Erzurumluoglu, A. Mesut
Liu, Mengzhen
Jackson, Victoria E.
Barnes, Daniel R.
Datta, Gargi
Melbourne, Carl A.
Young, Robin
Batini, Chiara
Surendran, Praveen
Jiang, Tao
Adnan, Sheikh Daud
Afaq, Saima
Agrawal, Arpana
Altmaier, Elisabeth
Antoniou, Antonis C.
Asselbergs, Folkert W.
Baumbach, Clemens
Bierut, Laura
Bertelsen, Sarah
Boehnke, Michael
Bots, Michiel L.
Brazel, David M.
Chambers, John C.
Chang-Claude, Jenny
Chen, Chu
Corley, Janie
Chou, Yi Ling
David, Sean P.
de Boer, Rudolf A.
de Leeuw, Christiaan A.
Dennis, Joe G.
Dominiczak, Anna F.
Dunning, Alison M.
Easton, Douglas F.
Eaton, Charles
Elliott, Paul
Evangelou, Evangelos
Faul, Jessica D.
Foroud, Tatiana
Goate, Alison
Gong, Jian
Grabe, Hans J.
Haessler, Jeff
Haiman, Christopher
Hallmans, Göran
Hammerschlag, Anke R.
Harris, Sarah E.
Smith, Jennifer A.
Zhou, Kaixin
Palmer, Colin N.A.
Liu, Dajiang J.
Howson, Joanna M. M.

October 2020

Smoking is a major heritable and modifiable risk factor for many diseases, including cancer, common ...

Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior.

Thorgeirsson, T.E.
Gudbjartsson, D.F.
Surakka, I.
Vink, J.M.
Amin, N.
Geller, F.
Sulem, P.
Rafnar, T.
Esko, T.
Walter, S.
Gieger, C.
Rawal, R.
Mangino, M.
Prokopenko, I.
Magi, R.
Keskitalo, K.
Gudjonsdottir, I.H.
Gretarsdottir, S.
Stefansson, H.
Thompson, J.R.
Aulchenko, Y.S.
Nelis, M.
Aben, K.K.H.
Heijer, M. den
Dirksen, A.
Ashraf, H.
Soranzo, N.
Valdes, A.M.
Steves, C.
Uitterlinden, A.G.
Hofman, A.
Tonjes, A.
Kovacs, P.
Hottenga, J.J.
Willemsen, G.
Vogelzangs, N.
Doring, A.
Dahmen, N.
Nitz, B.
Pergadia, M.L.
Saez, B.
Diego, V. De
Lezcano, V.
Garcia-Prats, M.D.
Ripatti, S.
Perola, M.
Kettunen, J.
Hartikainen, A.L.
Pouta, A.
Laitinen, J.
Isohanni, M.
Huei-Yi, S.
Allen, M.
Krestyaninova, M.
Hall, A.S.
Jones, G.T.
Rij, A.M. van
Mueller, T.
Dieplinger, B.
Haltmayer, M.
Jonsson, S.
Matthiasson, S.E.
Oskarsson, H.
Tyrfingsson, T.
Kiemeney, L.A.L.M.
Mayordomo, J.I.
Lindholt, J.S.
Pedersen, J.H.
Franklin, W.A.
Wolf, H.
Montgomery, G.W.
Heath, A.C.
Martin, N.G.
Madden, P.A.F.
Giegling, I.
Rujescu, D.
Jarvelin, M.R.
Salomaa, V.
Stumvoll, M.
Spector, T.D.
Wichmann, H.E.
Metspalu, A.
Samani, N.J.
Penninx, B.W.J.H.
Oostra, B.A.
Boomsma, D.I.
Tiemeier, H.
Duijn, C.M. van
Kaprio, J.
Gulcher, J.R.
McCarthy, M.I.
Peltonen, L.
Thorsteinsdottir, U.
Stefansson, K.

January 2010

Contains fulltext : 89305.pdf (publisher's version ) (Closed access)Smoking is a c...

Genetic Risk Can Be Decreased: Quitting Smoking Decreases and Delays Lung Cancer for Smokers With High and Low CHRNA5 Risk Genotypes - A Meta-analysis.

Chen, L.S.
Baker, T.
Hung, R.J.
Horton, A.
Culverhouse, R.
Hartz, S.
Saccone, N.
Cheng, I.
Deng, B.
Han, Y.
Hansen, H.M.
Horsman, J.
Kim, C.
Rosenberger, A.
Aben, K.K.
Andrew, A.S.
Chang, S.C.
Saum, K.U.
Dienemann, H.
Hatsukami, D.K.
Johnson, E.O.
Pande, M.
Wrensch, M.R.
McLaughlin, J.
Skaug, V.
van der Heijden, E.H.
Wampfler, J.
Wenzlaff, A.
Woll, P.
Zienolddiny, S.
Bickeböller, H.
Brenner, H.
Duell, E.J.
Haugen, A.
Brüske, I.
Kiemeney, L.A.
Lazarus, P.
Le Marchand, L.
Liu, G.
Mayordomo, J.
Risch, A.
Schwartz, A.G.
Teare, M.D.
Wu, X.
Wiencke, J.K.
Yang, P.
Zhang, Z.F.
Spitz, M.R.
Amos, C.I.
Bierut, L.J.

August 2016

BACKGROUND: Recent meta-analyses show that individuals with high risk variants in CHRNA5 on chromoso...

EBioMedicine / Genetic risk can be decreased : quitting smoking decreases and delays lung cancer for smokers with high and low CHRNA5 risk genotypes - a meta-analysis.

Chen, Li-Shiun
Baker, Timothy
Hung, Rayjean J.
Horton, Amy
Culverhouse, Robert
Hartz, Sarah
Saccone, Nancy
Cheng, Iona
Deng, Bo
Han, Younghun
Hansen, Helen M.
Horsman, Janet
Kim, Claire
Rosenberger, Albert
Aben, Katja K.
Andrew, Angeline S.
Chang, Shen-Chi
Saum, Kai-Uwe
Dienemann, Hendrick
Hatsukami, Dorothy K.
Johnson, Eric O.
Pande, Mala
Wrensch, Margaret R.
McLaughlin, John
Risch, Angela

January 2016

BACKGROUND: Recent meta-analyses show that individuals with high risk variants in CHRNA5 on chromoso...

Increased Genetic Vulnerability to Smoking at CHRNA5 in Early-Onset Smokers

Abstract

Extracted data

Increased Genetic Vulnerability to Smoking at CHRNA5 in Early-Onset Smokers

Abstract

Extracted data

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