The effects of exercise on cardiovascular biomarkers in patients with chronic heart failure
- Ahmad, Tariq
- Fiuzat, Mona
- Mark, Daniel B.
- Neely, Ben
- Neely, Megan
- Kraus, William E.
- Kitzman, Dalane W.
- Whellan, David J.
- Donahue, Mark
- Zannad, Faiez
- Piña, Ileana L.
- Adams, Kirkwood
- O'Connor, Christopher M.
- Felker, G. Michael
Publication date
January 2014
DOIAbstract
Exercise training is recommended for chronic heart failure (HF) patients to improve functional status and reduce risk of adverse outcomes. Elevated plasma levels of amino-terminal pro-brain natriuretic peptide (NT-proBNP), high-sensitivity C-reactive protein (hs-CRP), and cardiac troponin T (cTnT) are associated with increased risk of adverse outcomes in this patient population. Whether exercise training leads to improvements in biomarkers and how such improvements relate to clinical outcomes are unclear
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