Immunosuppression in Autoimmune Hepatitis: Is There an End Game?

Autoimmune hepatitis (AIH) is a rare, chronic disease associated with the development of cirrhosis and premature mortality. Current guidelines state that patients with AIH should receive induction therapy with corticosteroids or the combination of corticosteroids/azathioprine, followed by maintenance therapy with lower doses of steroids and/or azathioprine (1–3). However, the optimal strategy for the ongoing treatment beyond this point remains unclear