Potential Difference across Respiratory Epithelia in Cystic Fibrosis

To the Editor: In their paper describing increased electric potential difference across respiratory epithelia in cystic fibrosis (December 17 issue1) Knowles et al. mentioned that the time course of indomethacin's action on the bioelectric properties of respiratory epithelia was not well documented. This is not correct; we have previously reported details of indomethacin's effect on electrical properties and on transport of sodium and chloride across canine tracheal mucosa in vitro