The correlation of penicillinase production and bacteriophage adsorption of Staphylococcus aureus

"One of the very common organisms which displays degrees of antibiotic resistance is Staphylococcus Aureus, the organism selected for this study. Staphylococcus Aureus has a very wide distribution in nature, as it is found on the skin surface, in nasal passages, and in a variety of food products. Staphylococci may be the causative agents of boils, furuncles, osteomyelitis, secondary meningitis, septicemia, food poisoning and pneumonia. The virulence of Staphylococcus Aureus is primarily due to the production of metabolic products which have serious effects on physiological activities of the host. Perhaps the most reliable indication of Staphylococcus pathogenicity is the production of a procoagulase which unites with a factor in citrated or oxalated blood plasma to coagulate fibrinogen, causing fibrin to be deposited on the bacterial cell walls which protects them from phagocytosis.