The homotetrameric protein streptavidin (SA) binds the small molecule biotin with an extraordinarily high affinity. Their interaction is specific, long-lived and robust under a wide range of conditions. Biotin can readily be attached to proteins, nucleic acids or nanoparticles. This receptor-ligand system has thus found wide application in biotechnology, nanotechnology and medicine. Many modern diagnostic techniques, such as immunoassays, rely on the stable interaction of SA and biotin. In biophysics, the SA/biotin interaction serves as a popular anchoring tool to immobilize molecules or cells for force spectroscopy experiments using optical or magnetic tweezers, acoustic or atomic force microscopy. Within the last 25 years, a lot of effor...
Diffusion and molecular binding processes are indispensable for biological systems. A vital step tow...
The impact of nanotechnology in various aspects of the daily life is continually increasing, especi...
In dieser Arbeit wurde die Immobilisierung des Modellenzyms Penicillin G Acylase (EC 3.5.1.11) von E...
The homotetrameric protein streptavidin (SA) binds the small molecule biotin with an extraordinarily...
Protein-protein interactions play a crucial role in the development of drug delivery devices for the...
Molecular processes in organisms are often enabled by structural elements resilient to mechanical fo...
Most biomolecular interactions occur in aqueous environment. Therefore, one must consider the intera...
The majority of enzymes contains one or more organic or inorganic cofactor molecule(s) attached to t...
The following presents two approaches that use combined quantum mechanical/molecular mechanical (QM/...
This work developed during the first funding period of the subproject B05 in the framework of the in...
The basement membrane separates the epithelium from the stroma of any given barrier tissue and is es...
The motivation to understand intermolecular interactions on a fundamental level encourages natural s...
Enzymes are outstanding in their perfect 3D design through mastery of intrachain interaction of poly...
Neue Fortschritte im Verständnis des Entzündungsprozesses und dessen Beteiligung in einigen ernsten ...
In the present work the thermodynamics of protein adsorption to charged polyelectrolytes is explored...
Diffusion and molecular binding processes are indispensable for biological systems. A vital step tow...
The impact of nanotechnology in various aspects of the daily life is continually increasing, especi...
In dieser Arbeit wurde die Immobilisierung des Modellenzyms Penicillin G Acylase (EC 3.5.1.11) von E...
The homotetrameric protein streptavidin (SA) binds the small molecule biotin with an extraordinarily...
Protein-protein interactions play a crucial role in the development of drug delivery devices for the...
Molecular processes in organisms are often enabled by structural elements resilient to mechanical fo...
Most biomolecular interactions occur in aqueous environment. Therefore, one must consider the intera...
The majority of enzymes contains one or more organic or inorganic cofactor molecule(s) attached to t...
The following presents two approaches that use combined quantum mechanical/molecular mechanical (QM/...
This work developed during the first funding period of the subproject B05 in the framework of the in...
The basement membrane separates the epithelium from the stroma of any given barrier tissue and is es...
The motivation to understand intermolecular interactions on a fundamental level encourages natural s...
Enzymes are outstanding in their perfect 3D design through mastery of intrachain interaction of poly...
Neue Fortschritte im Verständnis des Entzündungsprozesses und dessen Beteiligung in einigen ernsten ...
In the present work the thermodynamics of protein adsorption to charged polyelectrolytes is explored...
Diffusion and molecular binding processes are indispensable for biological systems. A vital step tow...
The impact of nanotechnology in various aspects of the daily life is continually increasing, especi...
In dieser Arbeit wurde die Immobilisierung des Modellenzyms Penicillin G Acylase (EC 3.5.1.11) von E...